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    Human Anti-IL1R1 Recombinant Antibody (clone 26F5) (CAT#: HPAB-1862-FY)

    This product is a recombinant antibody that recognizes IL1R1. The monoclonal antibody 26F5 reacts with the epitope of IL1R1.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
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    Fc Engineering :
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    Other Requirements:
    We require custom production
    • Published Data
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Inhib

    Figure 1 Shows a graph illustrating the inhibitory effect of anti-IL-1R1 antibodies on IL-1R/IL-13/IL-1RAcP complex formation.

    Figure 1 Shows a graph illustrating the inhibitory effect of anti-IL-1R1 antibodies on IL-1R/IL-13/IL-1RAcP complex formation.

    Block

    Figure 2 Shows a graph representing the ability of anti-IL-1R1 antibodies to block IL-1β binding while not significantly interfering with binding of IL-1ra compared with IgG control.

    Figure 2 Shows a graph representing the ability of anti-IL-1R1 antibodies to block IL-1β binding while not significantly interfering with binding of IL-1ra compared with IgG control.

    Inhib

    Figure 3 Shows a graph showing inhibition of IL-6 production in primary human chondrocytes by anti-IL-1R1 antibodies identified herein and designated 15C4, 26F5, and 27F2 compared with IL-1ra.

    Figure 3 Shows a graph showing inhibition of IL-6 production in primary human chondrocytes by anti-IL-1R1 antibodies identified herein and designated 15C4, 26F5, and 27F2 compared with IL-1ra.


    Specifications

    • Host Species
    • Human
    • Type
    • Human IgG1
    • Specificity
    • Human IL1R1
    • Species Reactivity
    • Human
    • Clone
    • 26F5
    • Applications
    • Inhib, Block
    • Related Disease
    • Rheumatoid arthritis, osteoarthritis, and other inflammatory conditions

    Product Property

    • Purity
    • >95% as determined by SDS-PAGE and HPLC analysis
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS
    • Preservative
    • No preservatives
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Applications

    • Application Notes
    • The IL1R1 antibody has been reported in applications of Inhibition, Blocking.

    Target

    • Alternative Names
    • Interleukin 1 Receptor Type 1

    Related Resources

    • Related Diseases

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "Clone 26F5"

    See other products for "IL1R1"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibody Products Immunotoxin Products ADCC Enhanced Antibody Products Human Antibody Products Single Domain Antibody Products Neutralizing Antibody Products Rabbit Monoclonal Antibody Products ScFv Antibody Products Fab Antibody Products ScFv-Fc Chimera Products Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    MOB-1421z Mouse Anti-IL1R1 Recombinant Antibody (clone 32H6) WB, ELISA, FC, ICC, IHC Mouse IgG1
    HPAB-1863-FY Human Anti-IL1R1 Recombinant Antibody (clone 15C4) Inhib, Block Human IgG1
    HPAB-1864-FY Human Anti-IL1R1 Recombinant Antibody (clone 27F2) Inhib, Block Human IgG1
    VS3-QX596 Mouse Anti-IL1R1 Recombinant Antibody (clone D12-D2) WB, FC, ELISA Mouse IgG1
    VS3-QX597 Mouse Anti-IL1R1 Recombinant Antibody (clone 4D2D12) ELISA, FC Mouse IgG1

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