Human Anti-IL2 Recombinant Antibody (clone F5111.2) (CAT#: PABC-506)

This product is a recombinant Human antibody that can recognize IL2.

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Figure 1 Antibody F5111.2 inhibits upregulation of IL-2-induced proteins in CD8+ T cells but not Tregs in vitro.

Figure 1 Antibody F5111.2 inhibits upregulation of IL-2-induced proteins in CD8+ T cells but not Tregs in vitro.

Dose response of CD25 and FoxP3 expression on Treg, Tconv and CD8 cells following expansion of human PBMCs in the presence of hIL-2 (5 ng/ml)–F5111.2 complexes for five days. Representative results from one of five experiments are shown.

Trotta, E., Bessette, P. H., Silveria, S. L., Ely, L. K., Jude, K. M., Le, D. T., ... & Garcia, K. C. (2018). A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism. Nature medicine, 24(7), 1005.


  • Host Species
  • Human
  • Type
  • Human IgG1, λ
  • Specificity
  • Human IL2
  • Species Reactivity
  • Human
  • Clone
  • F5111.2
  • Applications
  • Inhib, ELISA, FC, FuncS
  • Related Disease
  • Autoimmune diseases and graft-versus-host disease

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.


  • Application Notes
  • This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Inhibition, Flow Cytometry and Functional Assay. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.


  • Alternative Names
  • IL-2; TCGF; lymphokine

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.


Download resources about recombinant antibody development and antibody engineering to boost your research.

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Deglycosylated Antibody (Non-glycosylated IgGs)

Chicken IgY Antibody

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BRD-0283MZ Chicken Anti-Interleukin-2 Polyclonal IgY WB, Indirect ELISA Chicken antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-1309CQ Mouse Anti-IL2 Recombinant Antibody (VMC195) FC, Block Mouse IgG1
NEUT-1315CQ Rat Anti-Il2 Recombinant Antibody (clone 1A12), Biotin Block, ELISA, WB Rat IgG2a

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1801 Rabbit Anti-IL2 Recombinant Antibody (clone DS1801AB) ICC, IHC-P, WB Rabbit IgG
MOR-4612 Rabbit Anti-IL2 Recombinant Antibody (clone TH125DS) WB, IHC-P Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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