This is an anti-human IL20 monoclonal antibody that can reduce IL20 mediated activation of both IL20R1/IL20R2 and IL22R1/IL20R2 receptor complexes. The antibody 5B7 can be used for treating various diseases and disorders, including autoimmune or inflammatory diseases or disorders.
Figure 1 Anti-IL-20 mAb 7E improved motor function and sensory function in SCI rats.
Data from one representative experiment of three independent experiments is shown.
Lee, J. S., Hsu, Y. H., Chiu, Y. S., Jou, I. M., & Chang, M. S. (2020). Anti-IL-20 antibody improved motor function and reduced glial scar formation after traumatic spinal cord injury in rats. Journal of Neuroinflammation, 17, 1-12.
Figure 2 IL-20 promoted astrocyte activation in HA cell line.
Data are expressed as mean ± SD and are representative of three independent experiments performed in triplicate.
Lee, J. S., Hsu, Y. H., Chiu, Y. S., Jou, I. M., & Chang, M. S. (2020). Anti-IL-20 antibody improved motor function and reduced glial scar formation after traumatic spinal cord injury in rats. Journal of Neuroinflammation, 17, 1-12.
Figure 3 OC-3 and OEC-M1 cells were treated with IL-20 for the indicated concentrations in serum-free medium for 30 minutes, and ROS generation was measured using flow cytometry.
Data from one representative experiment of three independent experiments is shown.
Hsu, Y. H., Wei, C. C., Shieh, D. B., Chan, C. H., & Chang, M. S. (2012). Anti–IL-20 Monoclonal Antibody Alleviates Inflammation in Oral Cancer and Suppresses Tumor Growth. Molecular Cancer Research, 10(11), 1430-1439.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-H34 | Anti-Human IL20 Recombinant Antibody (Fletikumab) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG4 - kappa |
TAB-561LC | Anti-human IL20 Recombinant Antibody (20A10) (TAB-561LC) | ELISA, Neut, SPR | Human antibody |
TAB-562LC | Anti-human IL20 Recombinant Antibody (2A11) (TAB-562LC) | ELISA, Neut, SPR | Human antibody |
TAB-563LC | Anti-human IL20 Recombinant Antibody (7D1) (TAB-563LC) | ELISA, Neut, SPR | Human antibody |
TAB-564LC | Anti-human IL20 Recombinant Antibody (6E11) (TAB-564LC) | ELISA, Neut | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0009CL | Human Anti-IL20 Recombinant Antibody (TAB-0009CL) | Inhib, IB, FC, RIA | Humanized Antibody |
TAB-0009CL-S(P) | Human Anti-IL20 Recombinant Antibody; scFv Fragment (TAB-0009CL-S(P)) | Inhib, ELISA, SPR | Humanized scFv |
TAB-0009CL-F(E) | Human Anti-IL20 Recombinant Antibody; Fab Fragment (TAB-0009CL-F(E)) | Inhib, ELISA, SPR | Humanized Fab |
TAB-565LC-S(P) | Anti-human IL20 scFv Fragment (FLB5M5) | ELISA | Humanized antibody |
TAB-565LC-F(E) | Anti-human IL20 Fab Fragment (FLB5M5) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-560LC | Rat Anti-IL20 Recombinant Antibody (TAB-560LC) | ELISA | Rat IgG |
TAB-560LC-S(P) | Rat Anti-IL20 Recombinant Antibody; scFv Fragment (TAB-560LC-S(P)) | ELISA | Rat scFv |
TAB-560LC-F(E) | Rat Anti-IL20 Recombinant Antibody; Fab Fragment (TAB-560LC-F(E)) | ELISA | Rat Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-0963CT | Recombinant Mouse anti-Human IL20 Monoclonal antibody (EML1475) | WB | |
HPAB-0008-LS | Human Anti-IL20 Recombinant Antibody (HPAB-0008-LS) | Inhib | Humanized lgG |
HPAB-0009-LS | Human Anti-IL20 Recombinant Antibody (HPAB-0009-LS) | Inhib | Humanized lgG |
HPAB-0723-CN | Human Anti-IL20 Recombinant Antibody (clone 15D2) | WB, ELISA, FC, IHC | Human IgG4, κ |
HPAB-0069-WJ | Human Anti-IL20 Recombinant Antibody (HPAB-0069-WJ) | WB, FC, IHC | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1324CQ | Rat Anti-Il20 Recombinant Antibody (clone CBL626) | Neut | Rat IgG2b |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4256 | Rabbit Anti-IL20 Recombinant Antibody (clone SI336DS) | ELISA | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0008-LS-F(E) | Human Anti-IL20 Recombinant Antibody; Fab Fragment (HPAB-0008-LS-F(E)) | Inhib | Humanized Fab |
HPAB-0009-LS-F(E) | Human Anti-IL20 Recombinant Antibody; Fab Fragment (HPAB-0009-LS-F(E)) | Inhib | Humanized Fab |
HPAB-0723-CN-F(E) | Human Anti-IL20 Recombinant Antibody (clone 15D2); Fab Fragment | WB, ELISA, Neut | Human Fab |
HPAB-0724-CN-F(E) | Human Anti-IL20 Recombinant Antibody (clone 5B7); Fab Fragment | WB, ELISA, Neut | Human Fab |
HPAB-0069-WJ-F(E) | Human Anti-IL20 Recombinant Antibody; Fab Fragment (HPAB-0069-WJ-F(E)) | IHC, ELISA, WB | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0008-LS-S(P) | Human Anti-IL20 Recombinant Antibody; scFv Fragment (HPAB-0008-LS-S(P)) | Inhib | Humanized scFv |
HPAB-0009-LS-S(P) | Human Anti-IL20 Recombinant Antibody; scFv Fragment (HPAB-0009-LS-S(P)) | Inhib | Humanized scFv |
HPAB-0723-CN-S(P) | Human Anti-IL20 Recombinant Antibody (clone 15D2); scFv Fragment | WB, ELISA, Neut | Human scFv |
HPAB-0724-CN-S(P) | Human Anti-IL20 Recombinant Antibody (clone 5B7); scFv Fragment | WB, ELISA, Neut | Human scFv |
HPAB-0069-WJ-S(P) | Human Anti-IL20 Recombinant Antibody; scFv Fragment (HPAB-0069-WJ-S(P)) | IHC, ELISA, WB | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-H34 | Afuco™ Anti-IL20 ADCC Recombinant Antibody (Fletikumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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