Human Anti-IL20 Recombinant Antibody (clone 15D2) (CAT#: HPAB-0723-CN)
This is an anti-human IL20 monoclonal antibody that can reduce IL20 mediated activation of both IL20R1/IL20R2 and IL22R1/IL20R2 receptor complexes. 15D2 inhibited cynomolgus IL20-induced as well as mouse IL20-induced proliferation of the BaF-3(hIL20R) cells, while hIL19 or hIL24-induced proliferation of BaF-3(hIL20R) was not inhibited by 15D2.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

(Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in parietal cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25802/ihc_selected.jpg

(Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25802/57430_B_7_5.jpg

(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25802/57430_A_9_3.jpg

(Cholangiocytes Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25802/57430_A_7_4.jpg

(Cells in tubules Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25802/57430_A_7_5.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000162891-IL20
Specifications
- Immunogen
- Human IL-20
- Host Species
- Human
- Type
- Human IgG4, κ
- Specificity
- Human IL20
- Species Reactivity
- Human, Cynomolgus, Mouse
- Clone
- 15D2
- Applications
- WB, ELISA, FC, IHC
- Related Disease
- Autoimmune, Inflammatory diseases
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The IL20 antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunohistochemistry, Flow Cytometry.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-H34 | Anti-Human IL20 Recombinant Antibody (Fletikumab) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG4 - kappa |
TAB-561LC-S(P) | Anti-human IL20 scFv Fragment (20A10) | ELISA | Human antibody |
TAB-562LC-S(P) | Anti-human IL20 scFv Fragment (2A11) | ELISA | Human antibody |
TAB-563LC-S(P) | Anti-human IL20 scFv Fragment (7D1) | ELISA | Human antibody |
TAB-564LC-S(P) | Anti-human IL20 scFv Fragment (6E11) | ELISA | Human antibody |
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