Mouse Anti-IL21R C-mannosylated glycopeptide Recombinant Antibody (clone 5G12)
CAT#: VS-0624-FY18
This product is a recombinant mouse antibody that has been created to bind to human DPEP3 protein. The mouse brain extract is utilized as the designated positive control for this antibody, which is employed in the western blot analysis of proteins extracted from mouse brain tissue.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/if_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_A_8_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_A_6_6.jpg
Normal Tissue
Figure 6 Bone marrow
Hematopoietic cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_B_6_4.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (Daudi, HDLM-2, Karpas-707, RH-30, RPMI-8226, U-266/70)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000103522-IL21R
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Specifications
- Immunogen
- KLH-conjugated peptide: C-mannosylated glycopeptide
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- C-mannosylated glycopeptide of human IL21R.
- Species Reactivity
- Human
- Clone
- 5G12
- Applications
- Western Blot
- Related Disease
- Immunodeficiency 56 and Immunodeficiency 31C
Product Property
- Clonality
- Monoclonal Antibody
- Purification
- Protein G purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Interleukin 21 Receptor C-mannosylated glycopeptide; IL21R C-mannosylated glycopeptide
- Gene ID
- 50615
- UniProt ID
- Q9HBE5
- Long Name
- Interleukin 21 Receptor C-mannosylated glycopeptide
- Sequence Similarities
- Belongs to the type I cytokine receptor family.
- Cellular Localization
- Membrane
- Post Translation Modifications
- C-mannosylated at Trp-214 in the WSXWS motif, the sugar chain makes extensive hydrogen bonds with Asn-73 sugar, and bridges the two fibronectin domains transforming the V-shaped receptor into an A-frame. (Q9HBE5-IL21R_HUMAN)
Glycosylation at Asn73, Asn97, Asn104, Asn125, Asn135, and Trp214 (NX_Q9HBE5 [NX_Q9HBE5-1])
Modification sites at PhosphoSitePlus (Q9HBE5)
Glycosylation from GlyGen (Q9HBE5) 6 sites
- Protein Refseq
- XP_011544159.1; XP_016878746.1; XP_047290136.1; XP_054236384.1; XP_054236385.1
- Function
- This is a receptor for interleukin-21.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
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- Product Name
Isotype Control
- CAT
- Product Name
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