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    Human Anti-IL21R Recombinant Antibody (clone ABS) (CAT#: HPAB-0669-CN)

    This is a monoclonal antibody which specifically binds to the human interleukin-21 receptor (IL-21R). The mAb 18A5 binds to IL-21R with high affinity and can be used to modulate immune responses in general, and those mediated by IL-21R in particular.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line A-431
    Figure 1 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/if_selected.jpg
    Normal Tissue
    Figure 2 Cerebral cortex
    Figure 2 Cerebral cortex
    (Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_B_7_5.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_A_8_3.jpg
    Figure 4 Kidney
    Figure 4 Kidney
    (Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_A_8_5.jpg
    Figure 5 Testis
    Figure 5 Testis
    (Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_A_6_6.jpg
    Figure 6 Bone marrow
    Figure 6 Bone marrow
    (Hematopoietic cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_B_6_4.jpg
    Figure 7 Lymph node
    Figure 7 Lymph node
    (Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_A_8_8.jpg
    RNA Expression
    Figure 8 RNA cell line category: Cell line enhanced (Daudi, HDLM-2, Karpas-707, RH-30, RPMI-8226, U-266/70)
    Figure 8 RNA cell line category: Cell line enhanced (Daudi, HDLM-2, Karpas-707, RH-30, RPMI-8226, U-266/70)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000103522-IL21R

    Specifications

    • Host Species
    • Human
    • Derivation
    • Phage display library
    • Type
    • Human IgG
    • Specificity
    • Human IL21R
    • Species Reactivity
    • Human, Cynomolgus, Mouse
    • Clone
    • ABS
    • Applications
    • ELISA, FC, Neut
    • Related Disease
    • Inflammatory disorders, autoimmune diseases, allergies, transplant rejection, hyperproliferative disorders of the blood, other immune system disorders

    Product Property

    • Purity
    • >95% as determined by SDS-PAGE and HPLC analysis
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Preservative
    • No preservatives
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • Interleukin 21 Receptor

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "Clone ABS"

    See other products for "IL21R"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibody Products Mouse Antibody Products Human Antibody Products Blocking Antibody Products Rabbit Monoclonal Antibody Products ScFv Antibody Products Fab Antibody Products Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    MOB-1347z Mouse Anti-IL21R Recombinant Antibody (clone 44B3) WB, IP, IF, ELISA Mouse IgG2a, κ
    MOB-0965CT Recombinant Mouse anti-Human IL21R Monoclonal antibody (NN0406-0A37) WB
    HPAB-AP685-YC Human Anti-IL21R Recombinant Antibody (clone C2) ELISA Human IgG
    VS-0723-WK200 Human Anti-IL21R Recombinant Antibody (VS-0723-WK200) ELISA, FC Chimeric (rabbit/human) IgG1
    VS-0624-FY18 Mouse Anti-IL21R C-mannosylated glycopeptide Recombinant Antibody (clone 5G12) WB Mouse IgG

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