Human Anti-IL23 Recombinant Antibody (clone ABT-874) (CAT#: HPAB-3397LY)

This product is an antibody that recognizes IL-23. The antibody ABT-874 can be used for immunoassay techniques such as: ELISA, FC, WB.


Specific Inquiry
  • Size:
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  • Purity:
  • Fc Engineering:
  • Published Data
  • Datasheet
  • MSDS
  • COA
FuncS

Figure 1 Mean percentage improvement in Psoriasis Area and Severity Index (PASI) scores from baseline.

Figure 1 Mean percentage improvement in Psoriasis Area and Severity Index (PASI) scores from baseline.

P<.001 for each ABT-874 treatment group compared with placebo at all time points. EOW indicates every other week.

Kimball, A. B., Gordon, K. B., Langley, R. G., Menter, A., Chartash, E. K., & Valdes, J. (2008). Safety and efficacy of ABT-874, a fully human interleukin 12/23 monoclonal antibody, in the treatment of moderate to severe chronic plaque psoriasis: results of a randomized, placebo-controlled, phase 2 trial. Archives of dermatology, 144(2), 200-207.


Specifications

  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • Human IgG
  • Specificity
  • Human IL23
  • Species Reactivity
  • Human
  • Clone
  • ABT-874
  • Applications
  • FuncS

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Functional Assay. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. should be carefully titrated in specific assays.

Target

  • Alternative Names
  • IL-23; Interleukin 23; IL12B; IL23A

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone ABT-874"

See other products for "IL23"

Human Antibody

CAT Product Name Application Type
TAB-419CL Human Anti-IL23 Recombinant Antibody (TAB-419CL) Inhib, FuncS Human IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-402CL Afuco™ Anti-IL23 Recombinant Antibody (AFC-402CL), ADCC Enhanced ELISA, WB Human IgG1

Neutralizing Antibody

Recombinant Antibody

CAT Product Name Application Type
HPAB-AP686-YC Mouse Anti-IL23 Recombinant Antibody (clone 8C92H6) ELISA Mouse IgG
HPAB-AP687-YC Human Anti-IL23 Recombinant Antibody (clone ch8C92H6) ELISA Chimeric (mouse/human) IgG
HPAB-AP688-YC Human Anti-IL23 Recombinant Antibody (clone A24AM18) ELISA, Neut Humanized (mouse/human) IgG
HPAB-AP689-YC Human Anti-IL23 Recombinant Antibody (clone A5M20) ELISA, Neut Humanized (mouse/human) IgG
HPAB-AP690-YC Human Anti-IL23 Recombinant Antibody (clone A5M21) ELISA, Neut Humanized (mouse/human) IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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