Anti-IL25 (clone W24V106) Recombinant Antibody Coupled Liposome (VS-1024-FY108) (CAT#: VS-1024-FY108)

• Potential Clinical Applications
• Glioma

• Clone
• W24V106

• Antibody Type
• IgG

• Antibody Host
• Human

• Antibody Reactivity
• Human

• Antibody Description
• This is a recombinant human monoclonal antibody designed to selectively bind to human interleukin-25 (IL-25). Interleukin-25 is a cytokine that plays a crucial role in the immune response, particularly in promoting the differentiation of T-helper 2 (Th2) cells and the subsequent production of other cytokines involved in allergic and inflammatory responses.

• Storage
• See in the COA

• Storage Shelf Time
• See in the COA

• Target
• IL25

• Introduction
• The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants.

• Alternative Names
• IL17E; interleukin-25; interleukin-17E

• Full Name
• Interleukin 25

• Gene ID
• 64806

• UniProt ID
• Q9H293

• Sequence Similarities
• Belongs to the IL-17 family.

• Cellular Localization
• Secreted

• Post Translation Modifications
• Glycosylation at Asn136 ( NX_Q9H293 [NX_Q9H293-1] )
  Modification sites at PhosphoSitePlus ( Q9H293 )
  Glycosylation from GlyGen (Q9H293) 2 sites, 1 O-linked glycan (1 site)

• Protein Refseq
• NP_073626.1; NP_758525.1

• Function
• Cytokine produced by various cells such as eosinophils, T-helper type 2 (Th2) cells or epithelial cells that plays a role in internal safety of adaptive immune responses by regulating cytokine production.

Select a product category from the dropdown menu below to view related products.