Recombinant Human Antibody clone 4C1, which is specific to IL2RA. The antibody is directed against an epitope of the alpha chain of the human Interleukin-2 receptor (IL-2R). The chimeric 4C1 Ab with specificity for the human IL-2R is a potentially interesting therapeutic reagent with potentialities for the treatment of T cell leukemia, auto-immune diseases, allografts and graft versus host settings.
Figure 1 Immunoblot analysis of concentrated supernatants (4Cls) and purified antibodies.
The supernatant was concentrated 6 times in Amicon Centriprep-30 and fractionated on 10% SDS-PAGE. For the detection of the light chain, a horseradish peroxidase-conjugated goat anti-human IgG kappa light chain antibody was used.
Figure 2 FACS analysis of the antigen binding of the chimeric (4Cl) antibody.
PHA-activated T cells were incubated with culture supernatant (S) of LICR (secreting an irrelevant human ab), with purified, FITC conjugated 2C8 (murine ab).
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1094z | Mouse Anti-IL2RA Recombinant Antibody (clone 18C9) | WB, ELISA, IF, IHC, FuncS | Mouse IgG1, κ |
PABL-242 | Human Anti-IL2RA Recombinant Antibody (clone 1H4) | WB, IHC, FuncS | Human IgG |
PABZ-020 | Human Anti-IL2RA Recombinant Antibody (clone CHI621) | Block | Chimeric (mouse/human) IgG |
PABZ-082 | Human Anti-IL2RA Recombinant Antibody (clone SDZ CHI621) | Block | Chimeric (mouse/human) IgG |
MOB-0351MZ | Recombinant Mouse Anti-Human IL2RA Antibody (clone BCT-2) | ELISA | Mouse antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
IAB-B073(A) | Recombinant Anti-human IL2RA Intrabody [(D-Arg)9] | IF, ELISA, FuncS | scFv-(D-Arg)9 |
IAB-B073(G) | Recombinant Anti-human IL2RA Intrabody [+36 GFP] | IF, FC, WB, FuncS | scFv-(+36GFP) |
IAB-B073(T) | Recombinant Anti-human IL2RA Intrabody [Tat] | WB, CO-IP, FuncS | scFv-Tat |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-004 | Anti-Human CD25 Recombinant Antibody (Basiliximab) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG1 - kappa |
PABX-030 | Recombinant Human Anti-CD25 Antibody (SDZCHII621) | Neut, FuncS | IgG |
PABX-030-F (E) | Recombinant Mouse Anti-CD25 Antibody Fab Fragment (SDZCHII621) | Neut, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-155 | Anti-Human CD25 Recombinant Antibody (Inolimomab) | IP, IF, FuncS, FC, Neut, ELISA, ICC | IgG1 - kappa |
TAB-641LC | Anti-human IL2RA Recombinant Antibody (Inolimomab) (TAB-641LC) | ELISA | |
TAB-641LC-S(P) | Anti-human IL2RA scFv Fragment (Inolimomab) | ELISA | |
TAB-641LC-F(E) | Anti-human IL2RA Fab Fragment (Inolimomab) | ELISA | |
PABX-029-S (P) | Recombinant Human Anti-CD25 Antibody scFv Fragment (Daclizumab) | WB, ELISA, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-L028E | anti-IL2RA immunotoxin RFT5 (IgG)-PE | Cytotoxicity assay, Functional assay | |
AGTO-L028D | anti-IL2RA immunotoxin RFT5 (IgG)-DT | Cytotoxicity assay, Functional assay | |
AGTO-L028R | anti-IL2RA immunotoxin RFT5 (IgG)-RTA | Cytotoxicity assay, Functional assay | |
AGTO-L078E | IL2-PE immunotoxin | Cytotoxicity assay, Functional assay | |
AGTO-L078D | IL2-DT immunotoxin | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBZ-020 | Mouse Anti-IL2RA Recombinant Antibody (clone CHI621); scFv Fragment | Block | Mouse scFv |
PSBL-608 | Mouse Anti-IL2RA Recombinant Antibody (clone RTF5); scFv Fragment | WB, FuncS | Mouse scFv |
HPAB-0559-WJ-S(P) | Human Anti-IL2RA Recombinant Antibody; scFv Fragment (HPAB-0559-WJ-S(P)) | ELISA, FC | Human scFv |
HPAB-0560-WJ-S(P) | Human Anti-IL2RA Recombinant Antibody; scFv Fragment (HPAB-0560-WJ-S(P)) | ELISA, FC | Human scFv |
HPAB-0561-WJ-S(P) | Human Anti-IL2RA Recombinant Antibody; scFv Fragment (HPAB-0561-WJ-S(P)) | ELISA, FC | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-642LC-S(P) | Human Anti-IL2RA Recombinant Antibody; scFv Fragment (TAB-642LC-S(P)) | ELISA, FC | Human scFv |
TAB-643LC-S(P) | Human Anti-IL2RA Recombinant Antibody; scFv Fragment (TAB-643LC-S(P)) | ELISA, FC | Human scFv |
TAB-644LC-S(P) | Human Anti-IL2RA Recombinant Antibody; scFv Fragment (TAB-644LC-S(P)) | ELISA, FC | Human scFv |
PABX-029 | Recombinant Human Anti-CD25 Antibody (Daclizumab) | WB, ELISA, FuncS, FC, Cyt | IgG |
PABX-029-F (E) | Recombinant Human Anti-CD25 Antibody Fab Fragment (Daclizumab) | WB, ELISA, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-646LC-S(P) | Anti-human IL2RA scFv Fragment (48M54S) | ELISA, FC | Humanized antibody |
TAB-647LC-S(P) | Anti-human IL2RA scFv Fragment (48M51L) | ELISA, FC | Humanized antibody |
TAB-648LC-S(P) | Anti-human IL2RA scFv Fragment (48V54S) | ELISA, FC | Humanized antibody |
TAB-649LC-S(P) | Anti-human IL2RA scFv Fragment (Dmab) | FC | Humanized antibody |
TAB-646LC-F(E) | Anti-human IL2RA Fab Fragment (48M54S) | ELISA, FC | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1344CQ | Mouse Anti-IL2RA Recombinant Antibody (clone B-B10) | FC, Neut, WB, IF | Mouse IgG1, κ |
NEUT-1345CQ | Mouse Anti-IL2RA Recombinant Antibody (clone CBL017) | Neut, WB, IHC | Mouse IgG1 |
NEUT-1346CQ | Mouse Anti-IL2RA Recombinant Antibody (clone CBL242) | ELISA, FC, Neut | Mouse IgG1, κ |
NEUT-1348CQ | Mouse Anti-IL2RA Recombinant Antibody (clone CBL726) | WB, IHC, ICC, Neut | Mouse IgG1 |
NEUT-1349CQ | Mouse Anti-IL2RA Recombinant Antibody (clone 1X27) | IHC, Neut, WB | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1350CQ | Mouse Anti-IL2RA Recombinant Antibody (clone 2R12) | Block, FC, ICC, IF, IHC, IP, WB | Mouse IgG1 |
NEUT-1356CQ | Rat Anti-Il2ra Recombinant Antibody (VMC199) | FC, IP, IHC, Block, Depletion | Rat IgG1, λ |
NEUT-1357CQ | Rat Anti-Il2ra Recombinant Antibody (clone 3C7) | FC, IP, Inhib | Rat IgG2b, κ |
NEUT-1358CQ | Rat Anti-Il2ra Recombinant Antibody (clone mAb0817) | Block, Depletion | Rat IgG1 |
NEUT-1359CQ | Rat Anti-Il2ra Recombinant Antibody (clone mAb0845) | Block, FC, IHC-Fr, IP | Rat IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1808 | Rabbit Anti-IL2RA Recombinant Antibody (clone DS1808AB) | IHC, ICC, IP | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0060-FY-F(E) | Human Anti-IL2RA Recombinant Antibody; Fab Fragment (HPAB-0060-FY-F(E)) | ELISA | Humanized Fab |
HPAB-0559-WJ-F(E) | Human Anti-IL2RA Recombinant Antibody; Fab Fragment (HPAB-0559-WJ-F(E)) | ELISA, FC | Human Fab |
HPAB-0560-WJ-F(E) | Human Anti-IL2RA Recombinant Antibody; Fab Fragment (HPAB-0560-WJ-F(E)) | ELISA, FC | Human Fab |
HPAB-0561-WJ-F(E) | Human Anti-IL2RA Recombinant Antibody; Fab Fragment (HPAB-0561-WJ-F(E)) | ELISA, FC | Human Fab |
HPAB-2113-FY-F(E) | Mouse Anti-IL2RA Recombinant Antibody (clone MAK179); Fab Fragment | Inhib | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-004 | Afuco™ Anti-IL2RA ADCC Recombinant Antibody (Basiliximab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-023 | Afuco™ Anti-IL2RA ADCC Recombinant Antibody (Daclizumab), ADCC Enhanced | ELISA, Neut, IF, IP, FC, FuncS | ADCC enhanced antibody |
AFC-TAB-155 | Afuco™ Anti-IL2RA ADCC Recombinant Antibody (Inolimomab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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