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    Rabbit Anti-IL2RA Recombinant Antibody (clone R03-3E2)

    CAT#: VS3-XY3393

    This product is a recombinant rabbit antibody targeting the human IL2RA (Interleukin 2 receptor subunit alpha), which is a regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. It recognizes and binds to human IL2RA. It has been determined using Immunohistochemistry-Paraffin, Immunocytochemistry or Immunofluorescence. The recommended dilutions of Immunohistochemistry-Paraffin and Immunofluorescence is 1/50-1/100 and 1/50-1/200, respectively.

    Gene Expression
    ❮
    Figure 1 Lymph node Figure 2 Tonsil Figure 3 RNA cell line category: Cell line enriched (HDLM-2)
    ❯

    Specifications

    • Host Species
    • Rabbit
    • Type
    • Rabbit IgG
    • Specificity
    • Human IL2RA
    • Species Reactivity
    • Human
    • Clone
    • R03-3E2
    • Related Disease
    • Immunodeficiency 41 With Lymphoproliferation And Autoimmunity and Type 1 Diabetes Mellitus 10

    Product Property

    • Clonality
    • Monoclonal
    • Aggregation
    • < 5%
    • Format
    • Liquid
    • Buffer
    • PBS (pH 7.4), 150 mM NaCl and 50% glycerol
    • Preservative
    • 0.02% sodium azide
    • Storage
    • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
    • Shipping
    • Ice packs

    Applications

    • Application Notes
    • IHC: 1/50-1/100
      IF: 1/50-1/200

    Target

    • Alternative Names
    • p55; CD25; IL2R; IMD41; TCGFR; IDDM10
    • Long Name
    • Interleukin 2 receptor subunit alpha
    • Cellular Localization
    • Membrane
    • Post Translation Modifications
    • Glycosylation at Asn70, Asn89, Thr218, Thr224, Thr229, and Thr237 (NX_P01589 [NX_P01589-1])
      Modification sites at PhosphoSitePlus (P01589)
      Glycosylation from GlyGen (P01589) 6 sites
    • Function
    • Receptor for interleukin-2.
      The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity.
      TREGs suppress the activation and expansion of autoreactive T-cells.
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    Downloadable Resources

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    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Datasheet

    Datasheet - VS3-XY3393.pdf

    MSDS

    MSDS - VS3-XY3393.pdf

    COA

    Certificate of Analysis Lookup

    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

    Lot Number:

    Protocol & Troubleshooting

    Immunofluorescence (IF)

    We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

    Isotype Control

    • CAT
    • Product Name

    Recommended Dilution Buffer

    • CAT
    • Product Name

    Secondary Antibody

    • CAT
    • Product Name

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