Afuco™ Anti-IL6 ADCC Recombinant Antibody (Enlimomab), ADCC Enhanced (CAT#: AFC-TAB-H26)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant Mouse antibody to Human IL6. R6.5 (BIRR-1, Enlimomab) is a murine IgG2a mAb to the human ICAM-1, inhibits leukocyte adhesion to the vascular endothelium.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72821/1350_G7_3_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72821/1350_G7_3_selected.jpg
Figure 2 IHC staining of human duodenum
(Immunohistochemical staining of human duodenum shows distinct cytoplasmic positivity in subsets of immune cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23406/54890_A_8_2_selected.jpg
(Immunohistochemical staining of human duodenum shows distinct cytoplasmic positivity in subsets of immune cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23406/54890_A_8_2_selected.jpg
Figure 3 Cerebral cortex
(Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23406/54890_B_7_5.jpg
(Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23406/54890_B_7_5.jpg
Figure 4 Urinary bladder
(Urothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23406/54890_A_4_5.jpg
(Urothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23406/54890_A_4_5.jpg
Figure 5 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23406/54890_A_9_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23406/54890_A_9_8.jpg
Figure 6 RNA cell line category: Group enriched (BJ hTERT+, GAMG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000136244-IL6
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000136244-IL6
Specifications
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- ADCC enhanced antibody
- Specificity
- ICAM1(intercellular adhesion molecule 1, ICAM-1, CD54) [Homo sapiens]
- Species Reactivity
- Human
- Clone
- Enlimomab
- Applications
- Neut, ELISA, IF, IP, FuncS, FC
- Conjugate
- Unconjugated
- Generic Name
- Enlimomab
- Related Disease
- Stroke
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Enlimomab; 142864-19-5; IL6; interleukin 6 (interferon, beta 2); IFNB2; interleukin-6; BSF2; HGF; HSF; IL 6; CDF; BSF-2; IFN-beta-2; interferon beta-2; interleukin BSF-2; hybridoma growth factor; CTL differentiation factor; B-cell stimulatory factor 2;
- Gene ID
- 3569
- UniProt ID
- P05231
Related Resources
Please refer to Enlimomab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Enlimomab.
Inflammatory Bowel Diseases
Rheumatoid Arthritis
Graft-versus-Host Disease
AGE-RAGE Signaling Pathway in Diabetic Complications
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "enlimomab"
Anti-Human ICAM1 Recombinant Antibody (Enlimomab)Recombinant Mouse antibody to human ICAM1. R6.5 (BIRR-1, Enlimomab) is a murine IgG2a mAb to the human ICAM-1, inhibits leukocyte adhesion to the vascular endothelium.
See other products for "IL6"
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-253 | Anti-Human IL-6 Recombinant Antibody (Olokizumab) | WB, ELISA, FC, IP, FuncS, IF, Neut | IgG4 - kappa |
| TAB-0172CL-S(P) | Human Anti-IL6 Recombinant Antibody; scFv Fragment (TAB-0172CL-S(P)) | ELISA, Block, In vivo | Human scFv |
| TAB-0173CL-S(P) | Human Anti-IL6 Recombinant Antibody; scFv Fragment (TAB-0173CL-S(P)) | ELISA, Block, In vivo | Human scFv |
| TAB-678LC-S(P) | Anti-human IL6 scFv Fragment (BA399) | ELISA, FC | Humanized antibody |
| TAB-678LC-F(E) | Anti-human IL6 Fab Fragment (BA399) | ELISA, FC | Humanized antibody |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0026CL | Human Anti-IL6 Recombinant Antibody (TAB-0026CL) | Elisa, In vivo, FuncS, Block | Chimeric (mouse/human) IgG |
| TAB-670LC | Anti-human IL6 Recombinant Antibody (NTS) (TAB-670LC) | ELISA, Inhib | Chimeric antibody (mouse/human) |
| TAB-670LC-S(P) | Anti-human IL6 scFv Fragment (NTS) | ELISA | Chimeric antibody (mouse/human) |
| TAB-670LC-F(E) | Anti-human IL6 Fab Fragment (NTS) | ELISA | Chimeric antibody (mouse/human) |
| VS3-WK1519 | Human Anti-IL6 Recombinant Antibody (clone CLLB8) | ELISA, FC | Chimeric (mouse/human) IgG1 |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0171CL | Mouse Anti-IL6 Recombinant Antibody (TAB-0171CL) | ELISA, Block, In vivo | Mouse IgG |
| TAB-0022CL-S(P) | Mouse Anti-IL6 Recombinant Antibody; scFv Fragment (TAB-0022CL-S(P)) | Elisa, In vivo, FuncS, Block | Mouse scFv |
| TAB-0023CL-S(P) | Mouse Anti-IL6 Recombinant Antibody; scFv Fragment (TAB-0023CL-S(P)) | Elisa, In vivo, FuncS, Block | Mouse scFv |
| TAB-0024CL-S(P) | Mouse Anti-IL6 Recombinant Antibody; scFv Fragment (TAB-0024CL-S(P)) | Elisa, In vivo, FuncS, Block | Mouse scFv |
| TAB-0025CL-S(P) | Mouse Anti-IL6 Recombinant Antibody; scFv Fragment (TAB-0025CL-S(P)) | Elisa, In vivo, FuncS, Block | Mouse scFv |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-680LC | Human Anti-IL6 Recombinant Antibody (TAB-680LC) | ELISA, FuncS | Human IgG1 |
| TAB-681LC | Human Anti-IL6 Recombinant Antibody (TAB-681LC) | ELISA, FuncS | Human IgG1 |
| TAB-682LC | Human Anti-IL6 Recombinant Antibody (TAB-682LC) | ELISA, FuncS | Human IgG1 |
| TAB-683LC | Anti-human IL6 Recombinant Antibody (IL6gk3-2) (TAB-683LC) | ELISA, SPR, FuncS | Human antibody |
| TAB-683LC-F(E) | Anti-human IL6 Fab Fragment (IL6gk3-2) | ELISA | Human antibody |
Fab Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-037LC | Recombinant Anti-Human IL6 Antibody (Fab glycosylation) | ELISA | Humanized antibody |
Deglycosylated Antibody (Non-glycosylated IgGs)
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-197LC | Recombinant Anti-Human IL6 Antibody (Non-glycosylated) | ELISA | Humanized antibody |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0284MZ | Chicken Anti-Interleukin-6 Polyclonal IgY | WB, Indirect ELISA | Chicken antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1450CQ | Mouse Anti-IL6 Recombinant Antibody (clone CBL596) | Neut | Mouse IgG2a |
| NEUT-1451CQ | Mouse Anti-IL6 Recombinant Antibody (clone CBL661) | Neut | Mouse IgG2b |
| NEUT-1452CQ | Mouse Anti-IL6 Recombinant Antibody (clone CBL553) | WB, Neut | Mouse IgG2a |
| NEUT-1453CQ | Mouse Anti-IL6 Recombinant Antibody (clone CBL615) | WB, Neut | Mouse IgG2b |
| NEUT-1454CQ | Mouse Anti-IL6 Recombinant Antibody (clone 1X45) | IHC, Neut | Mouse IgG2 |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1474CQ | Rat Anti-Il6 Recombinant Antibody (clone 32C11) | Block, ELISA, WB | Rat IgG2a |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1814 | Rabbit Anti-IL6 Recombinant Antibody (clone DS1814AB) | WB | Rabbit IgG |
| MOR-4277 | Rabbit Anti-IL6 Recombinant Antibody (clone SI360DS) | ELISA | Rabbit IgG |
| MOR-4622 | Rabbit Anti-IL6 Recombinant Antibody (clone TH135DS) | WB, ELISA | Rabbit IgG |
| MOR-4623 | Rabbit Anti-IL6 Recombinant Antibody (clone TH136DS) | WB | Rabbit IgG |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC3429 | PE-B8/Human IL6 (ILKQKIALD) MHC Tetramer | FCM | |
| MHC-LC3430 | APC-B8/Human IL6 (ILKQKIALD) MHC Tetramer | FCM |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0017-YC-F(E) | Human Anti-IL6 Recombinant Antibody; Fab Fragment (HPAB-0017-YC-F(E)) | ELISA, Block | Human Fab |
| HPAB-0674-CN-F(E) | Human Anti-IL6 Recombinant Antibody (clone 9C8-N68T-T83S); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-1250-FY-S(P) | Mouse Anti-IL6 Recombinant Antibody; scFv Fragment (HPAB-1250-FY-S(P)) | ELISA | Mouse scFv |
| HPAB-1251-FY-S(P) | Mouse Anti-IL6 Recombinant Antibody; scFv Fragment (HPAB-1251-FY-S(P)) | ELISA | Mouse scFv |
| HPAB-1252-FY-S(P) | Mouse Anti-IL6 Recombinant Antibody; scFv Fragment (HPAB-1252-FY-S(P)) | ELISA | Mouse scFv |
Neuroscience Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-043CN | Human Anti-IL6 Recombinant Antibody (NS-043CN) | ELISA, WB | Human IgG1 |
| NS-043CN-F(E) | Human Anti-IL6 Recombinant Antibody; Fab Fragment (NS-043CN-F(E)) | ELISA, WB | Human Fab |
| NS-043CN-S(P) | Human Anti-IL6 Recombinant Antibody; scFv Fragment (NS-043CN-S(P)) | ELISA, WB | Human scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0824-CN | Human Anti-IL6 Recombinant Antibody (clone Ab18) | ELISA | Human IgG |
| HPAB-0825-CN | Human Anti-IL6 Recombinant Antibody (clone 18E) | ELISA | Human IgG1 |
| HPAB-0030LY | Humanized Anti-IL6 Recombinant Antibody (HPAB-0030LY) | WB | Humanized IgG4 |
| MRO-0833-CN | Mouse Anti-IL6 Recombinant Antibody (clone 1-6) | WB, IHC, IF | Mouse IgG2b |
| MRO-0834-CN | Mouse Anti-IL6 Recombinant Antibody (clone 11-D4) | WB, IHC, IF, ELISA | Mouse IgG1 |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-239 | Afuco™ Anti-IL6 ADCC Recombinant Antibody (Elsilimomab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-097 | Afuco™ Anti-IL6 ADCC Recombinant Antibody (Sirukumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
| AFC-TAB-253 | Afuco™ Anti-IL6 ADCC Recombinant Antibody (Olokizumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP708-YC-S(P) | Human Anti-IL6 Recombinant Antibody (clone BA890); scFv Fragment | FuncS (Induce) | Human scFv |
| HPAB-AP709-YC-S(P) | Human Anti-IL6 Recombinant Antibody (clone BA399-2); scFv Fragment | ELISA, Inhib, FuncS | Human scFv |
| HPAB-1105WJ-S(P) | Mouse Anti-IL6 Recombinant Antibody (clone CLB8); scFv Fragment | Neut, ELISA | Mouse scFv |
| HPAB-S0076-YC-S(P) | Rabbit Anti-IL6 Recombinant Antibody; scFv Fragment (HPAB-S0076-YC-S(P)) | ELISA, WB, Block, FuncS | Rabbit scFv |
| HPAB-S0077-YC-S(P) | Human Anti-IL6 Recombinant Antibody; scFv Fragment (HPAB-S0077-YC-S(P)) | ELISA, Block | Human scFv |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-S0166-YC | Camelid Anti-IL6 Recombinant Single Domain Antibody (clone 6D5) | ELISA | Camelid VHH |
| HPAB-S0167-YC | Camelid Anti-IL6 Recombinant Single Domain Antibody (clone 8F2) | ELISA | Camelid VHH |
| HPAB-S0168-YC | Camelid Anti-IL6 Recombinant Single Domain Antibody (clone 6B12) | ELISA, Inhib | Camelid VHH |
| HPAB-S0169-YC | Camelid Anti-IL6 Recombinant Single Domain Antibody (clone 7G4) | ELISA, Inhib | Camelid VHH |
| HPAB-S0170-YC | Camelid Anti-IL6 Recombinant Single Domain Antibody (clone 7G5) | ELISA, Inhib | Camelid VHH |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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