DrugMonitor™ Anti-Infliximab Antibody (VS-1224-YC603) (CAT#: VS-1224-YC603)
Infliximab is a chimeric monoclonal IgG1 antibody targeting tumor necrosis factor-alpha (TNF-α), composed of human constant (75%) and murine variable (25%) regions, approved for intravenous treatment of various inflammatory disorders. The DrugMonitor™ Anti-Infliximab Antibody (VS-1224-YC603) is an anti-drug antibody (ADA) against Infliximab. This drug-based antibody is raised in mice immunized with the Infliximab. The anti-Infliximab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Infliximab in samples.
Specific Inquiry
Specifications
- Host Animal
- Mouse
- Specificity
- Infliximab
- Target
- Infliximab
- Immunogen
- Infliximab
- Type
- Mouse IgG
- Purity
- >95%
- Purification
- Protein G
- Applications
- ELISA, PK/PD, ADA control
- Format
- Liquid
- Concentration
- Batch-dependent
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for 1-2 weeks and at -20°C for 1 year. Avoid repeated freezing and thawing.
- Generic name
- Infliximab
- Drug Weight
- 144190.3 Da
- Formula
- C₆₄₂₈H₉₉₁₂N₁₆₉₄O₁₉₈₇S₄₆
- Related Disease
- Inflammatory disorders
Downloads
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See other products for "Infliximab"
Anti-Human TNF Recombinant Antibody (Infliximab)Recombinant monoclonal antibody to Human TNF. Infliximab (INN; trade name Remicade) is a monoclonal antibody against tumour necrosis factor alpha (TNF-α) used to treat autoimmune diseases.
Infliximab was approved for the treatment of psoriasis, Crohn's disease, ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis, and ulcerative colitis.
Afuco™ Anti-TNF ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-006)This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to Human TNF. It is a monoclonal antibody against tumour necrosis factor alpha (TNF-α) used to treat autoimmune diseases.
See other products for "Infliximab"
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MHC Tetramer Products for Other Applications
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF121 | DRB1*07:01/Mouse Infliximab Heavy chain (EWVAEIRSKSINSAT) MHC Monomer | MHC Multimer | |
| MHC-YF122 | DRB1*15:01/Mouse Infliximab Heavy chain (EWVAEIRSKSINSAT) MHC Monomer | MHC Multimer |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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