AbPlus™ Anti-INSR Magnetic Beads (1.B.109) (CAT#: VS-0424-XY155)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magrose bead (> 50 μmol/mL gel)

• Bead Ligand
• Anti-INSR specific antibody (1.B.109)

• Target
• INSR

• Immunogen
• Purified human alpha subunit of INSR

• Target Species
• Human

• Antibody Clone
• 1.B.109

• Bead Capacity
• 20-30 mg/mL binding antibody

• Bead size
• 10-37 μm

• Stability
• pH 2-14

• Format
• 20% Suspension

• Buffer
• PBS, pH 7.4, with 1% BSA

• Preservative
• 0.03% Proclin 300

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene.

• Alternative Names
• INSR; insulin receptor; HHF5; CD220; IR

• Gene ID
• 3643

• UniProt ID
• P06213

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