Human Anti-INSR Recombinant Antibody (clone IR 18-146) (CAT#: FAMAB-1171CQ)
IR 18-146 is a recombinant human antibody that recognizes INSR. IR 18-146 was purified by affinity chromatography and can be used in Immunoprecipitation and stimulation assays.
Specific Inquiry
FC
Figure 1 Mutant INSR is expressed at the cell surface and bound by anti-INSR antibody.
Stacked overlay single parameter histograms showing cell surface expression of INSR mutants bound by antibodies 18-146, as determined by flow
cytometry.
Brierley, G. V., Siddle, K., & Semple, R. K. (2018). Evaluation of anti-insulin receptor antibodies as potential novel therapies for human insulin receptoropathy using cell culture models. Diabetologia, 61(7), 1662-1675.
Specifications
- Immunogen
- Purified human placental insulin receptor
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Human INSR
- Species Reactivity
- Human
- Clone
- IR 18-146
- Applications
- FC
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Flow Cytometry.
Target
Related Resources
PPAR Signaling Pathway
Type I Diabetes Mellitus
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone IR 18-146"
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Rat Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-441CL | Human Anti-INSR Recombinant Antibody (TAB-441CL) | ELISA | Human IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-246 | Mouse Anti-INSR Recombinant Antibody (clone 83-7) | WB, ELISA, FuncS | Mouse IgG |
| MRO-0845-CN | Rabbit Anti-INSR Recombinant Antibody (clone CBACN-308) | WB, IF | Rabbit IgG |
| HPAB-2351LY | Human Anti-INSR Recombinant Antibody (HPAB-2351LY) | ELISA, WB, FC, FuncS | Humanized IgG |
| HPAB-2352LY | Human Anti-INSR Recombinant Antibody (HPAB-2352LY) | ELISA, WB, FC, FuncS | Humanized IgG |
| HPAB-2353LY | Human Anti-INSR Recombinant Antibody (HPAB-2353LY) | ELISA, WB | Humanized IgG |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-711LC | Human Anti-INSR Recombinant Antibody (TAB-711LC) | ELISA, FC, FuncS | Human IgG |
| TAB-712LC | Human Anti-INSR Recombinant Antibody (TAB-712LC) | ELISA, FC, Agonist, FuncS | Human IgG |
| TAB-711LC-F(E) | Human Anti-INSR Recombinant Antibody; Fab Fragment (TAB-711LC-F(E)) | ELISA, FC | Human Fab |
| PABX-124-S (P) | Recombinant Mouse Anti-IR Antibody scFv Fragment (Fab83-14) | Neut, FuncS | scFv |
| PABX-125-S (P) | Recombinant Mouse Anti-IR Antibody scFv Fragment (Fab83-7) | WB, ELISA, FuncS | scFv |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-124 | Recombinant Mouse Anti-IR Antibody (Fab83-14) | Neut, FuncS | IgG |
| PABX-125 | Recombinant Mouse Anti-IR Antibody (Fab83-7) | WB, ELISA, FuncS | IgG |
| PABX-124-F (E) | Recombinant Mouse Anti-IR Antibody Fab Fragment (Fab83-14 ) | Neut, FuncS | Fab |
| PABX-125-F (E) | Recombinant Mouse Anti-IR Antibody Fab Fragment (Fab83-7 ) | WB, ELISA, FuncS | Fab |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC1205 | PE-H-2Kb/Mouse Insr (GNYSFYAL) MHC Tetramer | FCM | |
| MHC-LC1206 | APC-H-2Kb/Mouse Insr (GNYSFYAL) MHC Tetramer | FCM | |
| MHC-LC1207 | BV421-H-2Kb/Mouse Insr (GNYSFYAL) MHC Tetramer | FCM |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1533CQ | Mouse Anti-INSR Recombinant Antibody (clone 1.B.109) | Inhib, IP | Mouse IgG2a |
| NEUT-1535CQ | Mouse Anti-INSR Recombinant Antibody (clone 47-9) | FC, Block, WB | Mouse IgG1 |
| NEUT-1536CQ | Mouse Anti-INSR Recombinant Antibody (clone 18-44) | FC, ICC, IF, Block, FuncS, IP, WB | Mouse IgG2b |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1534CQ | Mouse Anti-INSR Recombinant Antibody (clone 29B4) | IP, Neut | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1844 | Rabbit Anti-INSR Recombinant Antibody (clone DS1844AB) | ICC, IP, WB | Rabbit IgG |
| MOR-4630 | Rabbit Anti-INSR Recombinant Antibody (clone TH143DS) | WB | Rabbit IgG |
| MOR-4688 | Rabbit Anti-INSR Recombinant Antibody (clone TH202DS) | WB, FC | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2351LY-F(E) | Human Anti-INSR Recombinant Antibody; Fab Fragment (HPAB-2351LY-F(E)) | ELISA, WB | Humanized Fab |
| HPAB-2352LY-F(E) | Human Anti-INSR Recombinant Antibody; Fab Fragment (HPAB-2352LY-F(E)) | ELISA, WB | Humanized Fab |
| HPAB-2353LY-F(E) | Human Anti-INSR Recombinant Antibody; Fab Fragment (HPAB-2353LY-F(E)) | ELISA, WB | Humanized Fab |
| HPAB-2354LY-F(E) | Human Anti-INSR Recombinant Antibody; Fab Fragment (HPAB-2354LY-F(E)) | ELISA, WB | Humanized Fab |
| HPAB-2355LY-F(E) | Human Anti-INSR Recombinant Antibody; Fab Fragment (HPAB-2355LY-F(E)) | ELISA, WB | Humanized Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2351LY-S(P) | Human Anti-INSR Recombinant Antibody; scFv Fragment (HPAB-2351LY-S(P)) | ELISA, WB | Humanized scfv |
| HPAB-2352LY-S(P) | Human Anti-INSR Recombinant Antibody; scFv Fragment (HPAB-2352LY-S(P)) | ELISA, WB | Humanized scfv |
| HPAB-2353LY-S(P) | Human Anti-INSR Recombinant Antibody; scFv Fragment (HPAB-2353LY-S(P)) | ELISA, WB | Humanized scfv |
| HPAB-2354LY-S(P) | Human Anti-INSR Recombinant Antibody; scFv Fragment (HPAB-2354LY-S(P)) | ELISA, WB | Humanized scfv |
| HPAB-2355LY-S(P) | Human Anti-INSR Recombinant Antibody; scFv Fragment (HPAB-2355LY-S(P)) | ELISA, WB | Humanized scfv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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