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    Rabbit Anti-INSR Recombinant Antibody (VS13-YC592) (CAT#: VS13-YC592)

    The Rabbit Anti-INSR Recombinant Antibody is specific for human and rat INSR. INSR, involving insulin binding, links to severe insulin resistance syndromes, with mutations affecting glucose regulation pathways through receptor kinase activities, presenting multiple transcript forms. The anti-INSR antibody can be used for Western blot (1/500-1/2000), Immunocytochemistry (1/100-1/500), Immunofluorescence (1/100-1/500).

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    • Size:

    • Conjugation:

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    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
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    Conjugation :
    Fc Engineering :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & vesicles.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36303/737_C10_2_selected.jpg
    Figure 2 IHC staining of human liver
    Figure 2 IHC staining of human liver
    (Immunohistochemical staining of human liver shows moderate cytoplasmic positivity in hepatocytes.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36302/ihc_selected.jpg
    Figure 3 IF staining of human cell line A-431
    Figure 3 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36303/836_E10_2_blue_red_green.jpg
    Normal Tissue
    Figure 4 Colon
    Figure 4 Colon
    (landular cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36302/112008_A_9_3.jpg
    Figure 5 Liver
    Figure 5 Liver
    (Hepatocytes
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36302/112008_A_8_4.jpg
    Figure 6 Kidney
    Figure 6 Kidney
    (Cells in tubules
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36302/112008_A_7_5.jpg
    Figure 7 Testis
    Figure 7 Testis
    (Leydig cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36302/112008_A_6_6.jpg
    Figure 8 Skeletal muscle
    Figure 8 Skeletal muscle
    (Myocytes
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36302/112008_B_3_6.jpg
    Figure 9 Lymph node
    Figure 9 Lymph node
    (Germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36302/112008_A_8_8.jpg
    RNA Expression
    Figure 10 RNA cell line category: Cell line enhanced (Karpas-707, U-266/70)
    Figure 10 RNA cell line category: Cell line enhanced (Karpas-707, U-266/70)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000171105-INSR
    Figure 10 RNA cell line category: Cell line enhanced (Karpas-707, U-266/70)
    Figure 10 RNA cell line category: Cell line enhanced (Karpas-707, U-266/70)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000171105-INSR

    Specifications

    • Immunogen
    • Recombinant human insulin receptor, aa 930-970.
    • Host Species
    • Rabbit
    • Type
    • Rabbit IgG
    • Specificity
    • Human and Rat INSR
    • Species Reactivity
    • Human, Rat
    • Applications
    • WB, ICC, IF
    • Conjugate
    • NONE

    Product Property

    • Clonality
    • Monoclonal
    • Purification
    • Protein A purified
    • Format
    • Liquid
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
    • Preservative
    • 0.05% Sodium azide
    • Storage
    • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Shipping with ice pack.

    Applications

    • Application Notes
    • Western blot (WB): 1/500-1/2000
      Immunocytochemistry (ICC): 1/100-1/500
      Immunofluorescence (IF): 1/100-1/500

    Target

    • Alternative Names
    • Insulin Receptor
    • Long Name
    • Insulin Receptor
    • Cellular Localization
    • Cell membrane
    • Function
    • Signal transduction

    Recommended Products

    Secondary Antibody

    Isotype Control

    Related Resources

    • Related Signaling Pathways
    • Related Diseases

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "INSR"

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    CAT Product Name Application Type
    MOB-1236z Mouse Anti-INSR Recombinant Antibody (clone 25F8) ELISA, FC, ICC, IF, IHC, FuncS Mouse IgG1, κ
    PABZ-083 Mouse Anti-INSR Recombinant Antibody (clone 83-14) WB, FuncS Mouse IgG
    MOB-0984CT Recombinant Mouse anti-Human INSR Monoclonal antibody (94-8) ELISA, FC, IHC-P, IP
    FAMAB-1171CQ Human Anti-INSR Recombinant Antibody (clone IR 18-146) FC Human IgG1
    VS3-WK571 Rabbit Anti-INSR Recombinant Antibody (clone JM22-38) WB, ELISA Rabbit IgG

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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