Mouse Anti-IRAK3 Recombinant Antibody (clone 5C3D6) (CAT#: VS7-0425-WR147)
This product is a mouse IgG1 recombinant antibody that binds to human IRAK3. The antibody 5C3D6 recognizes a specific amino acid domain of human IRAK3 (AA: 454-596). It can be used for ICC assay.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SiHa
(Immunofluorescent staining of human cell line SiHa shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43097/if_selected.jpg
(Immunofluorescent staining of human cell line SiHa shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43097/if_selected.jpg
Figure 2 IHC staining of human tonsil
(Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in germinal center cells and non-germinal center cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43097/ihc_selected.jpg
(Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in germinal center cells and non-germinal center cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43097/ihc_selected.jpg
Figure 3 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43097/97682_A_8_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43097/97682_A_8_3.jpg
Figure 4 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43097/97682_A_8_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43097/97682_A_8_5.jpg
Figure 5 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43097/97682_A_6_6.jpg
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43097/97682_A_6_6.jpg
Figure 6 Bone marrow
(Hematopoietic cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43097/97682_B_4_4.jpg
(Hematopoietic cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43097/97682_B_4_4.jpg
Figure 7 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, HEL, HL-60, NB-4, THP-1, U-937)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000090376-IRAK3
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000090376-IRAK3
Specifications
- Immunogen
- Recombinant human IRAK3 (AA: 454-596) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human IRAK3
- Species Reactivity
- Human
- Clone
- 5C3D6
- Molecule Class
- Kinase
- Applications
- ICC
- Conjugate
- Unconjugated
- Related Disease
- Inflammatory diseases; Autoimmune diseases
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunocytochemistry: 1:100 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- ASRT5; IRAKM
- Gene ID
- 11213
- UniProt ID
- Q9Y616
- Long Name
- Interleukin 1 Receptor Associated Kinase 3
- Cellular Localization
- Cytoplasm; Nucleus
- Post Translation Modifications
- Disulfide bond; Phosphoprotein
- Protein Refseq
- NP_001135995
- Function
- ATP binding; magnesium ion binding; nucleotide binding; protein binding; protein heterodimerization activity; protein homodimerization activity; protein serine/threonine kinase activity;
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0993CT | Recombinant Mouse anti-Human IRAK3 Monoclonal antibody (EML1219) | WB | |
| MRO-0866-CN | Recombinant Rabbit Anti-IRAK3 Monoclonal Antibody (CBACN-318) | WB, IP | Rabbit IgG |
| VS3-WK129 | Mouse Anti-IRAK3 Recombinant Antibody (clone G2-G9) | WB, ELISA | Mouse IgG1 |
| VS3-WK1231 | Rabbit Anti-IRAK3 Recombinant Antibody (VS3-WK1231) | WB, IP | Rabbit IgG |
| VS7-0425-WR148 | Mouse Anti-IRAK3 Recombinant Antibody (clone 6G9G2) | IHC, ICC, FC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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