Mouse Anti-IRAK4 Monoclonal Antibody (VS7-0425-WR149) (CAT#: VS7-0425-WR149)
This product is a mouse IgG antibody that binds to human IRAK4. The antibody 1H3E62 can be used for IHC, ICC, adnd FC assays. It cross reacts with mouse and monkey.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane, cytosol & microtubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16685/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane, cytosol & microtubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16685/if_selected.jpg
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoli, cytosol & microtubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22077/621_E10_5_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoli, cytosol & microtubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22077/621_E10_5_selected.jpg
Figure 3 IHC staining of human colon
(Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells and smooth muscle cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16685/ihc_selected.jpg
(Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells and smooth muscle cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16685/ihc_selected.jpg
Figure 4 IHC staining of human breast
(Immunohistochemical staining of human breast shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22077/ihc_selected.jpg
(Immunohistochemical staining of human breast shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22077/ihc_selected.jpg
Figure 5 Cerebral cortex
(nuclear Neuronal cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22077/49420_B_8_5.jpg
(nuclear Neuronal cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22077/49420_B_8_5.jpg
Figure 6 Pancreas
(Exocrine glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Pancreatic endocrine cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22077/49420_A_1_3.jpg
(Exocrine glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Pancreatic endocrine cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22077/49420_A_1_3.jpg
Figure 7 Kidney
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16685/37917_A_7_5.jpg
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16685/37917_A_7_5.jpg
Figure 8 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22077/49420_A_6_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22077/49420_A_6_6.jpg
Figure 9 RNA cell line category: Cell line enhanced (U-937)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000198001-IRAK4
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000198001-IRAK4
Specifications
- Immunogen
- Recombinant human IRAK4 fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human IRAK4
- Species Reactivity
- Human, Mouse, Monkey
- Molecule Class
- Kinase
- Applications
- WB, IHC-P, IF, FC, ELISA
- Conjugate
- Unconjugated
- Related Disease
- Immunodeficiency; Inflammatory diseases; Autoimmune diseases.
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- 1 mg/mL
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunohistochemistry: 1:200 - 1:1000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- IPD1; IMD67; REN64; IRAK-4; NY-REN-64
- Gene ID
- 51135
- UniProt ID
- Q9NWZ3
- Long Name
- Interleukin 1 Receptor Associated Kinase 4
- Cellular Localization
- Cytoplasm
- Post Translation Modifications
- Acetylation; Phosphoprotein
- Protein Refseq
- NP_001107654
- Function
- ATP binding; interleukin-1 receptor binding; magnesium ion binding; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; protein serine/threonine kinase activity;
Recommended Products
Isotype Control
Secondary Antibody
Related Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "IRAK4"
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IgG Antibody Products
Mouse Antibody Products
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Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2079z | Mouse Anti-IRAK4 Recombinant Antibody (clone 27A3) | WB, ELISA, FC, IHC | Mouse IgG1 |
| MOB-0992CT | Recombinant Mouse anti-Human IRAK4 Monoclonal antibody (A8A8) | ELISA, IHC-P, WB | |
| ZG-0770J | Rabbit Anti-IRAK4 Recombinant Antibody (clone 10H4) | ELISA, WB, FC | Rabbit IgG |
| VS3-FY761 | Recombinant Rabbit Anti-IRAK4 Antibody (clone R01-1B2) | WB, IHC-Fr, IHC-P, ICC, IF | Rabbit IgG |
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