Mouse Anti-ITGA2B Recombinant Antibody (clone 5B12) (CAT#: VS2-QX2)
This product is a mouse antibody that recognizes CD41.5B12 can be used to detect human platelet antigens (HPA) on the GpIIb/IIIa complex.5B12 will detect platelets in human tissue and also label megakaryocytes in sections or smears prepared from human bone marrow.5B12 does not inhibit aggregation by Ionophore, ADP collagen or risocetin.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HEL
(Immunofluorescent staining of human cell line HEL shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31169/1877_G7_33_selected.jpg
(Immunofluorescent staining of human cell line HEL shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31169/1877_G7_33_selected.jpg
Figure 2 Bone marrow
(Hematopoietic cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31168/73889_B_5_4.jpg
(Hematopoietic cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31168/73889_B_5_4.jpg
Figure 3 RNA cell line category: Group enriched (HEL, HMC-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000005961-ITGA2B
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000005961-ITGA2B
Specifications
- Immunogen
- Normal human platelets
- Host Species
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- CD41
- Species Reactivity
- Human
- Clone
- 5B12
- Applications
- IF
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- BDPLT16; BDPLT2; CD41; CD41B; GP2B; GPIIb; GT; GTA; HPA3; PPP1R93
- Gene ID
- 3674
- UniProt ID
- P08514
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| TAB-015-F(E) | Anti-Human CD41 Recombinant Antibody Fab Fragment (Abciximab) | IP, IF, FuncS, FC, Neut, ELISA, ICC | Fab - G1 - kappa |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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