Mouse Anti-ITGA2B Recombinant Antibody (clone p256.1) (CAT#: VS3-CJ501)
This product is a mouse antibody that recognizes human ITGA2B (CD41).
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HEL
(Immunofluorescent staining of human cell line HEL shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31169/1877_G7_33_selected.jpg
(Immunofluorescent staining of human cell line HEL shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31169/1877_G7_33_selected.jpg
Figure 2 Bone marrow
(Hematopoietic cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31168/73889_B_5_4.jpg
(Hematopoietic cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31168/73889_B_5_4.jpg
Figure 3 RNA cell line category: Group enriched (HEL, HMC-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000005961-ITGA2B
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000005961-ITGA2B
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Human ITGA2B (CD41)
- Species Reactivity
- Human
- Clone
- p256.1
- Applications
- IF, FC
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- PBS, pH 7.3.
- Preservative
- 0.02% Sodium Azide
- Storage
- Store at 4°C for one year. Do not freeze.
- Shipping
- Shipped at 4°C
Applications
- Application Notes
- This antibody has been tested for use in Immunofluorescence, Flow Cytometry.
Target
- Alternative Names
- GT; GT1; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; BDPLT16; PPP1R93
- Gene ID
- 3674
- UniProt ID
- P08514
- Sequence Similarities
- Belongs to the integrin alpha chain family.
- Cellular Localization
- Membrane
- Protein Refseq
- NP_000410.2
- Function
- Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
Recommended Products
Secondary Antibody
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "ITGA2B"
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-015-F(E) | Anti-Human CD41 Recombinant Antibody Fab Fragment (Abciximab) | IP, IF, FuncS, FC, Neut, ELISA, ICC | Fab - G1 - kappa |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-740 | Human Anti-ITGA2B Recombinant Antibody (clone RUC-2); Fab Fragment | Block | Human Fab |
| HPAB-0275-YC-F(E) | Mouse Anti-ITGA2B Recombinant Antibody; Fab Fragment (HPAB-0275-YC-F(E)) | ELISA, FuncS | Mouse Fab |
| HPAB-0276-YC-F(E) | Mouse Anti-ITGA2B Recombinant Antibody; Fab Fragment (HPAB-0276-YC-F(E)) | FuncS | Mouse Fab |
| HPAB-0277-YC-F(E) | Human Anti-ITGA2B Recombinant Antibody; Fab Fragment (HPAB-0277-YC-F(E)) | FuncS | Humanized Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-740 | Human Anti-ITGA2B Recombinant Antibody (clone RUC-2); scFv Fragment | Block | Human scFv |
| HPAB-0275-YC-S(P) | Mouse Anti-ITGA2B Recombinant Antibody; scFv Fragment (HPAB-0275-YC-S(P)) | ELISA, FuncS | Mouse scFv |
| HPAB-0276-YC-S(P) | Mouse Anti-ITGA2B Recombinant Antibody; scFv Fragment (HPAB-0276-YC-S(P)) | FuncS | Mouse scFv |
| HPAB-0277-YC-S(P) | Human Anti-ITGA2B Recombinant Antibody; scFv Fragment (HPAB-0277-YC-S(P)) | FuncS | Humanized scFv |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1546CQ | Recombinant Mouse Anti-ITGA2B Antibody (HIP8) | CyTOF, FuncS, FC, IFC, IHC, Neut | IgG1, κ |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1547CQ | Recombinant Mouse Anti-ITGA2B Antibody (PAC1) | FC, IP, WB, BL | IgM, κ |
| NEUT-1548CQ | Recombinant Mouse Anti-ITGA2B Antibody (A2A9/6) | FC, BL, IP | IgG2a, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1872 | Hi-Affi™ Recombinant Rabbit Anti-ITGA2B Monoclonal Antibody (DS1872AB) | WB, IHC | IgG |
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0578CQ | Recombinant Mouse Anti-Human ITGA2B Antibody (1E6) | ELISA | IgG2a |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS1-YJ27 | Mouse Anti-ITGA2B Recombinant Antibody (clone M148) | FC | Mouse IgG1 |
| VS1-YJ28 | Mouse Anti-ITGA2B Recombinant Antibody (clone M148), FITC | FC | Mouse IgG1 |
| VS3-XY887 | Mouse Anti-ITGA2B Recombinant Antibody, FITC (clone 4AHIP8) | FC, IHC, IF | Mouse IgG1 |
| VS3-XY888 | Mouse Anti-ITGA2B Recombinant Antibody, PE (clone 4AHIP8) | FC, IHC, IF | Mouse IgG1 |
| VS3-XY889 | Mouse Anti-ITGA2B Recombinant Antibody, PE-Cy5 (clone 4AHIP8) | FC, IHC, IF | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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