Camelid Anti-ITGA3 Recombinant Single Domain Antibody (HPAB-0778-YJ-VHH)
CAT#: HPAB-0778-YJ-VHH
This product is a recombinant Llama single domain antibody that recognizes Human ITGA3. It could inhibit VLA-3 mediated cell-matrix adhesion.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18594/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18594/204_G7_1_blue_red_green.jpg
Subcellular Location
Figure 3 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18594/203_G7_1_blue_red_green.jpg
Normal Tissue
Figure 4 Lung
Alveolar cells type I
Staining: High
Intensity: Strong
Quantity: 75%-25%
Alveolar cells type II
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8572/23996_A_2_4.jpg
Normal Tissue
Figure 5 Colon
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8572/23996_A_9_3.jpg
Normal Tissue
Figure 6 Liver
Hepatocytes
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8572/23996_A_9_4.jpg
Normal Tissue
Figure 7 Kidney
Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8572/23996_A_7_5.jpg
Normal Tissue
Figure 8 Testis
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8572/23996_A_6_6.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (HBEC3-KT, hTERT-RPE1, RPTEC TERT1, U-87 MG, WM-115)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000005884-ITGA3
❮
❯
Specifications
- Host Species
- Camelid
- Type
- Camelid VHH
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- HPAB-0778-YJ-VHH
- Applications
- ELISA, Inhib
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Inhibition.
Target
- Alternative Names
- VL3A; CD49C; FRP-2; GAPB3; ILNEB; MSK18; VCA-2; VLA3a; GAP-B3; integrin alpha-3; CD49 antigen-like family member C; alpha 3 subunit of VLA-3 receptor; antigen CD49C; antigen identified by monoclonal antibody J143; galactoprotein B3; integrin alpha 3; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor); testicular tissue protein Li 96; testicular tissue protein Li 98; very late activation protein 3 receptor, alpha-3 subunit
- Gene ID
- 3675
- UniProt ID
- P26006
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for HPAB-0778-YJ-VHH. Click the button above to contact us or submit your feedback about this product.
High Purity VHH Antibody
The quality of this VHH antibody is impressive, with purity over 95% by SDS-PAGE and HPLC. It recognizes human ITGA3 with high specificity. We appreciate the recombinant production in CHO/HEK293 systems, which provides a level of consistency that is essential for our research on integrin alpha chain functions.
Potent Inhibitor of Adhesion
This Camelid single domain antibody was incredibly effective at inhibiting VLA-3 mediated cell-matrix adhesion in our assays. Its small size likely allows it to access epitopes that larger antibodies might miss. We are very pleased with its performance in both inhibition assays and ELISA detection of ITGA3.
Q&As
-
What is unique about the structure of this antibody?
A: This product is a recombinant Camelid single domain antibody (VHH), also known as a VHH fragment. This format allows for unique binding properties. It recognizes Human ITGA3 and is capable of inhibiting VLA-3 mediated cell-matrix adhesion.
-
Can this antibody be used for inhibition studies?
A: Yes, this antibody has been reported for use in Inhibition assays (Inhib) as well as ELISA. It specifically targets the alpha 3 subunit of the VLA-3 receptor, which interacts with extracellular matrix proteins like laminin.
View the frequently asked questions answered by Creative Biolabs Support.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "ITGA3"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1157z | Mouse Anti-ITGA3 Recombinant Antibody (clone 20D11) | WB, IP, IF, IHC, ELISA | Mouse IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2262MZ | Recombinant Mouse Anti-Human ITGA3 Antibody (clone 28D7), FITC-Conjugated | FC | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0294MZ | Chicken Anti-ITGA3 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0016-CN | Human Anti-ITGA3 Recombinant Antibody (HPAB-0016-CN) | ELISA | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0017-CN | Human Anti-ITGA3 Recombinant Antibody (HPAB-0017-CN) | ELISA | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0018-CN | Mouse Anti-ITGA3 Recombinant Antibody (clone ITGa3-VM2) | IF, ELISA, IP | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0016-CN-S(P) | Human Anti-ITGA3 Recombinant Antibody; scFv Fragment (HPAB-0016-CN-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0017-CN-S(P) | Human Anti-ITGA3 Recombinant Antibody; scFv Fragment (HPAB-0017-CN-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0018-CN-S(P) | Mouse Anti-ITGA3 Recombinant Antibody (clone ITGa3-VM2); scFv Fragment | IF, ELISA, IP | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0016-CN-F(E) | Human Anti-ITGA3 Recombinant Antibody; Fab Fragment (HPAB-0016-CN-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0017-CN-F(E) | Human Anti-ITGA3 Recombinant Antibody; Fab Fragment (HPAB-0017-CN-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0018-CN-F(E) | Mouse Anti-ITGA3 Recombinant Antibody (clone ITGa3-VM2); Fab Fragment | IF, ELISA, IP | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1659LY-S(P) | Mouse Anti-ITGA3 Recombinant Antibody; scFv Fragment (HPAB-1659LY-S(P)) | ELISA | Mouse scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1659LY-F(E) | Mouse Anti-ITGA3 Recombinant Antibody; Fab Fragment (HPAB-1659LY-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1461-FY | Recombinant Anti-ITGA3 Single Domain Antibody (HPAB-1461-FY) | ELISA, FC | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1154 | Anti-ITGA3 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC678 | Recombinant Anti-ITGA3 Vesicular Antibody, EV Displayed (VS-0425-YC678) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3622 | Anti-Human ITGA3 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: WB, Neut, ELISA, IF, IP, FuncS, FC
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
