Human Anti-ITGAV Recombinant Antibody (clone 3F2) (CAT#: HPAB-1768-FY)
This product is a recombinant antibody that recognizes ITGAV. The monoclonal antibody 3F2 reacts with the epitope of ITGAV.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
ELISA
Figure 1 ELISA analysis of the wild type anti-EphA2 antibody 3F2 and the 3F2 I332E (3F2-1M) and 3F2 S239D/A330L/I332E (3F2-3M) Fc variants binding to FcγRIIIA tetramer.
ELISA
Figure 2 ELISA analysis of the wild type anti-EphA2 antibody 3F2 and the 3F2 I332E (3F2-1M) and 3F2 S239D/A330L/I332E (3F2-3M) Fc variants binding to FcγRIIIA monomer.
FC
Figure 3 FACS analysis of anti-EphA2 antibody 3F2-WT, 3F2-1M and 3F2- 3M binding to cells via Fc -domain interactions.
FC
Figure 4 FACS analysis of anti-EphA2 antibody 3F2-WT, 3F2-1M and 3F2- 3M binding to cells via Fc -domain interactions.
ADCC
Figure 5 Cell-based ADCC assay of anti-EphA2 antibody 3F2 and the 3F2- IM and 3F2-3M Fc variants to target cells expressing high (T231, A549) levels of EphA2.
In each assay the antibody concentration ranged from 0.02 ug/ml to 2 μg/ml. E:T ratios varied from 12.5:1 to 100:1 depending on the assay.
ADCC
Figure 6 Cell-based ADCC assay of anti-EphA2 antibody 3F2 and the 3F2- IM and 3F2-3M Fc variants to target cells expressing high (T231, A549) levels of EphA2.
In each assay the antibody concentration ranged from 0.02 μg/ml to 2 μg/ml. E:T ratios varied from 12.5:1 to 100:1 depending on the assay.
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG
- Specificity
- Human ITGAV
- Species Reactivity
- Human
- Clone
- 3F2
- Applications
- ELISA, FC, ADCC
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The ITGAV antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Flow Cytometry, Antibody-dependent Cell-mediated Cytotoxicity.
ADCC: 0.02 μg/ml to 2 μg/ml.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-076 | Anti-Human CD51 Recombinant Antibody (TAB-076) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG1 - kappa |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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