Human Anti-ITGAV Recombinant Antibody (clone 3F2) (CAT#: HPAB-1768-FY)
This product is a recombinant antibody that recognizes ITGAV. The monoclonal antibody 3F2 reacts with the epitope of ITGAV.
Specific Inquiry
ELISA
Figure 1 ELISA analysis of the wild type anti-EphA2 antibody 3F2 and the 3F2 I332E (3F2-1M) and 3F2 S239D/A330L/I332E (3F2-3M) Fc variants binding to FcγRIIIA tetramer.
ELISA
Figure 2 ELISA analysis of the wild type anti-EphA2 antibody 3F2 and the 3F2 I332E (3F2-1M) and 3F2 S239D/A330L/I332E (3F2-3M) Fc variants binding to FcγRIIIA monomer.
FC
Figure 3 FACS analysis of anti-EphA2 antibody 3F2-WT, 3F2-1M and 3F2- 3M binding to cells via Fc -domain interactions.
FC
Figure 4 FACS analysis of anti-EphA2 antibody 3F2-WT, 3F2-1M and 3F2- 3M binding to cells via Fc -domain interactions.
ADCC
Figure 5 Cell-based ADCC assay of anti-EphA2 antibody 3F2 and the 3F2- IM and 3F2-3M Fc variants to target cells expressing high (T231, A549) levels of EphA2.
In each assay the antibody concentration ranged from 0.02 ug/ml to 2 μg/ml. E:T ratios varied from 12.5:1 to 100:1 depending on the assay.
ADCC
Figure 6 Cell-based ADCC assay of anti-EphA2 antibody 3F2 and the 3F2- IM and 3F2-3M Fc variants to target cells expressing high (T231, A549) levels of EphA2.
In each assay the antibody concentration ranged from 0.02 μg/ml to 2 μg/ml. E:T ratios varied from 12.5:1 to 100:1 depending on the assay.
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG
- Specificity
- Human ITGAV
- Species Reactivity
- Human
- Clone
- 3F2
- Applications
- ELISA, FC, ADCC
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The ITGAV antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Flow Cytometry, Antibody-dependent Cell-mediated Cytotoxicity.
ADCC: 0.02 μg/ml to 2 μg/ml.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 3F2"
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Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-076 | Anti-Human CD51 Recombinant Antibody (Intetumumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG1 - kappa |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H01 | Anti-Human ITGAV Recombinant Antibody (Abituzumab) | Inhib, Agonist | IgG2 - kappa |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-250 | Mouse Anti-ITGAV Recombinant Antibody (clone 17E6) | WB, ELISA, FuncS | Mouse IgG |
| MRO-0852-CN | Recombinant Rabbit Anti-ITGAV Monoclonal Antibody (CBACN-313) | WB, FC | Rabbit IgG |
| PABS-0202 | Mouse Anti-ITGAV Recombinant Antibody (clone 8B8) | ELISA | Mouse IgG |
| PABS-0203 | Mouse Anti-ITGAV Recombinant Antibody (clone 68) | ELISA | Mouse IgG |
| ZG-0041U | Rabbit Anti-ITGAV Recombinant Antibody (clone 5G3) | ELISA, WB, IHC | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-250 | Mouse Anti-ITGAV Recombinant Antibody (clone 17E6); scFv Fragment | WB, ELISA, FuncS | Mouse scFv |
| HPAB-1767-FY-F(E) | Human Anti-ITGAV Recombinant Antibody (clone 12G3); scFv Fragment | Cyt, ELISA | Humanized scFv |
| HPAB-1768-FY-F(E) | Human Anti-ITGAV Recombinant Antibody (clone 3F2); scFv Fragment | Cyt, ELISA | Humanized scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-250 | Mouse Anti-ITGAV Recombinant Antibody (clone 17E6); Fab Fragment | WB, ELISA, FuncS | Mouse Fab |
| HPAB-1767-FY-S(P) | Human Anti-ITGAV Recombinant Antibody (clone 12G3); Fab Fragment | Cyt, ELISA | Humanized Fab |
| HPAB-1768-FY-S(P) | Human Anti-ITGAV Recombinant Antibody (clone 3F2); Fab Fragment | Cyt, ELISA | Humanized Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-191-S (P) | Recombinant Mouse Anti-αVβ3 Ectodomain Antibody scFv Fragment (17E6) | Neut, FuncS | scFv |
| PABX-191-F (E) | Recombinant Mouse Anti-αVβ3 Ectodomain Antibody Fab Fragment (17E6) | Neut, FuncS | Fab |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1537CQ | Recombinant Mouse Anti-ITGAV Antibody (272-17E6) | Inhib, ICC/IF, BL, FC, ELISA, IP | IgG1 |
| NEUT-1577CQ | Recombinant Mouse Anti-ITGAV Antibody (13C2) | FC, IHC-Fr, ICC, IP, ELISA, Depletion, BL, Adhesion | IgG1, κ |
| NEUT-1578CQ | Recombinant Mouse Anti-ITGAV Antibody (NKI-M9) | FC, IF, ELISA, BL, IP | IgG2a, κ |
| NEUT-1579CQ | Recombinant Mouse Anti-ITGAV Antibody (10D5) | IP, FC, BL | IgG2a |
| NEUT-1580CQ | Recombinant Mouse Anti-ITGAV Antibody (27.1) | ICC/IF, FC, IP, IHC-Fr, BL | IgG1 |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1582CQ | Recombinant Rat Anti-Itgav Antibody (RMV-7) | FC, FuncS, IP, Neut | IgG1, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1880 | Hi-Affi™ Recombinant Rabbit Anti-ITGAV Monoclonal Antibody (DS1880AB) | WB, FC | IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-076 | Afuco™ Anti-ITGAV ADCC Recombinant Antibody (Intetumumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| AFC-TAB-H01 | Afuco™ Anti-ITGAV ADCC Recombinant Antibody (Abituzumab), ADCC Enhanced | ELISA, IP, FC, FuncS, IF, Neut | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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