Human Anti-ITGAV Recombinant Antibody (clone 3F2) (CAT#: HPAB-1768-FY)

This product is a recombinant antibody that recognizes ITGAV. The monoclonal antibody 3F2 reacts with the epitope of ITGAV.

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ELISA

Figure 1 ELISA analysis of the wild type anti-EphA2 antibody 3F2 and the 3F2 I332E (3F2-1M) and 3F2 S239D/A330L/I332E (3F2-3M) Fc variants binding to FcγRIIIA tetramer.

ELISA

Figure 2 ELISA analysis of the wild type anti-EphA2 antibody 3F2 and the 3F2 I332E (3F2-1M) and 3F2 S239D/A330L/I332E (3F2-3M) Fc variants binding to FcγRIIIA monomer.

FC

Figure 3 FACS analysis of anti-EphA2 antibody 3F2-WT, 3F2-1M and 3F2- 3M binding to cells via Fc -domain interactions.

FC

Figure 4 FACS analysis of anti-EphA2 antibody 3F2-WT, 3F2-1M and 3F2- 3M binding to cells via Fc -domain interactions.

ADCC

Figure 5 Cell-based ADCC assay of anti-EphA2 antibody 3F2 and the 3F2- IM and 3F2-3M Fc variants to target cells expressing high (T231, A549) levels of EphA2.

In each assay the antibody concentration ranged from 0.02 ug/ml to 2 μg/ml. E:T ratios varied from 12.5:1 to 100:1 depending on the assay.

ADCC

Figure 6 Cell-based ADCC assay of anti-EphA2 antibody 3F2 and the 3F2- IM and 3F2-3M Fc variants to target cells expressing high (T231, A549) levels of EphA2.

In each assay the antibody concentration ranged from 0.02 μg/ml to 2 μg/ml. E:T ratios varied from 12.5:1 to 100:1 depending on the assay.


Specifications

  • Host Species
  • Human
  • Derivation
  • Humanized
  • Type
  • Humanized IgG
  • Specificity
  • Human ITGAV
  • Species Reactivity
  • Human
  • Clone
  • 3F2
  • Applications
  • ELISA, FC, ADCC
  • Related Disease
  • Cancer

Applications

  • Application Notes
  • The ITGAV antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Flow Cytometry, Antibody-dependent Cell-mediated Cytotoxicity.
    ADCC: 0.02 μg/ml to 2 μg/ml.

Target

  • Alternative Names
  • Integrin Subunit Alpha V

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

See other products for "ITGAV"

See other products for "Clone 3F2"


For Research Use Only. Not For Clinical Use.

* Abbreviations
3D IHC3D Immunohistochemistry
ActivActivation
AgonistAgonist
ApopApoptosis
BABioassay
BIBioimaging
BlockBlocking
Cell ScreeningCell Screening
SeparationCell Separation
ChIPChromatin Immunoprecipitation
CMCDComplement Mediated Cell Depletion
CostimCostimulation
CytCytotoxicity
DepletionDepletion
DBDot Blot
EMElectron Microscopy
ELISAEnzyme-linked Immunosorbent Assay
ELISPOTEnzyme-linked Immunosorbent Spot
FCFlow Cytometry
FuncSFunctional Assay
GSGel Super Shift Assay
HAHemagglutination
IAImmunoassay
IBImmunoblotting
ICCImmunocytochemistry
IDImmunodiffusion
IFImmunofluorescence
IHCImmunohistochemistry
IHC-FrImmunohistochemistry-Frozen
IHC-PImmunohistochemistry-Paraffin
REImmunohistology - Resin Sections
IPImmunoprecipitation
IRMAImmunoradiometric Assay
SHIn situ hybridization
InhibInhibition
ICFCIntracellular Staining for Flow Cytometry
KO/KD-WBKnockout/Knockdown target confirmation by Western Blot
Live cell imagingLive cell imaging
CyTOF®Mass Cytometry
MeDIPMethylated DNA Immunoprecipitation
MultiplexMultiplex bead-based assay
NeutNeutralization
PPProtein Purification
PGProteogenomics
RIRadial Immunodiffusion
RIARadioimmunoassay
StimStimulation
SPRSurface Plasmon Resonance
TCTissue Culture
TBTurbidimetry
WBWestern Blot

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