CytoStream™ Hamster Anti-Itgax Recombinant Antibody (VS13-YC601) (CAT#: VS13-YC601)
The CytoStream™ Hamster Anti-Itgax Recombinant Antibody is specific for mouse Itgax. Itgax is predicted to enable binding activities for integrins and receptor tyrosine kinases, influencing gene expression and myelination regulation. It's involved in virus defense responses, located on the plasma membrane's external side, and expressed in the heart and hemolymphoid system. The anti-Itgax antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (5 μL per 1x 10⁶ cells).
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 High expression in spleen
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4723/14046_B_7_4_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4723/14046_B_7_4_selected.jpg
Figure 2 Low expression in cerebral cortex
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4723/14046_B_9_5_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4723/14046_B_9_5_val_selected.jpg
Figure 3 Cerebral cortex
(Glial cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4458/14042_B_7_5.jpg
(Glial cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4458/14042_B_7_5.jpg
Figure 4 Lymph node
(Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4458/14042_A_7_8.jpg
(Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4458/14042_A_7_8.jpg
Figure 5 Spleen
(Cells in red pulp Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in white pulp Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4458/14042_B_8_4.jpg
(Cells in red pulp Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in white pulp Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4458/14042_B_8_4.jpg
Figure 6 RNA cell line category: Cell line enriched (HMC-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000140678-ITGAX
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000140678-ITGAX
Specifications
- Immunogen
- Recombinant mouse CD11c.
- Host Species
- Armenian hamster
- Type
- Armenian hamster IgG
- Specificity
- Mouse Itgax
- Species Reactivity
- Mouse
- Applications
- FC
- Conjugate
- APC
- Related Disease
- Hairy Cell Leukemia; Sporotrichosis
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS with 1% BSA.
- Preservative
- 0.05% Proclin 300
- Storage
- Store at 4°C for 12 months away from light. Do not freeze.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Flow cytometry (FC): 5 μL per 1x 10⁶ cells
Target
- Alternative Names
- Cd11c, Cr4, N418
- Gene ID
- 16411
- UniProt ID
- Q9QXH4
- Long Name
- integrin alpha X
- Cellular Localization
- Membrane
- Protein Refseq
- XP_011544154.1; XP_011544156.1
- Function
- Integrin alpha-X/beta-2 is a receptor for fibrinogen.
It recognizes the sequence G-P-R in fibrinogen.
It mediates cell-cell interaction during inflammatory responses.
It is especially important in monocyte adhesion and chemotaxis.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3769z | Mouse Anti-ITGAX Recombinant Antibody (clone 20F12) | WB, ELISA, FC | Mouse IgG1 |
| MOB-0381CT | Recombinant Mouse anti-Human ITGAX Monoclonal antibody (4.0) | FC | |
| HPAB-0304-CN | Hamster Anti-ITGAX Recombinant Antibody (clone N418) | WB, ELISA, IHC | Hamster IgG |
| VS3-CJ775 | Rabbit Anti-ITGAX Recombinant Antibody (VS3-CJ775) | WB, IHC, IP | Rabbit IgG |
| VS3-XY3401 | Rabbit Anti-ITGAX Recombinant Antibody (clone R06-5A7) | WB, IHC-P, ICC, IF, IP | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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