Mouse Anti-ITGB2 Recombinant Antibody (clone 60.3) (CAT#: FAMAB-0203CQ)
Recombinant Mouse Antibody clone 60.3, which is specific to CD18. mAb 60.3 interacts with the CD 18 component of the β2 integrins. 60.3 has potential clinical application in blocking the neutrophil-mediated organ damage which occurs following a myocardial infarct or hemorrhagic shock.
Specific Inquiry
Figure 1 Comparison of in vitro adhesion by activated peripheral blood leukocytes from a cat affected by feline leukocyte adhesion deficiency and a control cat.
Purified leukocytes from the proband and control cat were bound to fibrinogen in the absence (No PMA) or presence of the CD11/CD18 activator phorbol 12-myristate 13-acetate (PMA). Adhesion of activated leukocytes was completely blocked by anti-CD18 antibody 60.3 in the control cat, demonstrating CD18 specificity. The vertical lines indicate the SD of triplicate data.
Bauer Jr, T. R., Pratt, S. M., Palena, C. M., Raj, K., & Giger, U. (2017). Feline leukocyte adhesion (CD 18) deficiency caused by a deletion in the integrin β2 (ITGB 2) gene. Veterinary clinical pathology, 46(3), 391-400.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG2a, κ
- Specificity
- Human CD18
- Species Reactivity
- Human
- Clone
- 60.3
- Applications
- ELISA, WB, Block
Product Property
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-099 | Recombinant Anti-Human ITGB2 VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-044 | Anti-Human ITGB2 Recombinant Antibody (Rovelizumab) | Neut, ELISA, IF, IP, FuncS, FC, IHC | IgG4 |
| TAB-154-F(E) | Anti-Human CD18 Recombinant Antibody F(ab')2 Fragment( Erlizumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG1 |
| TAB-1582CL | Anti-Human ITGB2 Recombinant Antibody (Hu23F2G (also known as LeukArrest and Rovelizumab)) | IP, FuncS | Humanized antibody |
| TAB-1582CL-S(P) | Anti-Human ITGB2 Recombinant Antibody scFv Fragment (Hu23F2G (also known as LeukArrest and Rovelizumab)) | Inhib | Humanized antibody |
| TAB-1582CL-F(E) | Anti-Human ITGB2 Recombinant Antibody Fab Fragment (Hu23F2G (also known as LeukArrest and Rovelizumab)) | Inhib | Humanized antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1581CL | Anti-Human ITGB2 Recombinant Antibody (23F2G) | Inhib | |
| TAB-1581CL-S(P) | Anti-Human ITGB2 Recombinant Antibody scFv Fragment (23F2G) | Inhib | |
| TAB-1581CL-F(E) | Anti-Human ITGB2 Recombinant Antibody Fab Fragment (23F2G) | Inhib |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0298MZ | Chicken Anti-ITGB2 Polyclonal IgY | WB | Chicken antibody |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1590CQ | Recombinant Mouse Anti-ITGB2 Antibody (MEM-48) | BL, FC, IHC-Fr, IHC-P, IP, WB | IgG1 |
| NEUT-1591CQ | Recombinant Mouse Anti-ITGB2 Antibody (TS1/18) | BL, FC, ICC/IF, IHC, WB | IgG1 |
| NEUT-1592CQ | Recombinant Mouse Anti-ITGB2 Antibody (YFC118.12) | FC, BL | IgG1, κ |
| NEUT-1593CQ | Recombinant Mouse Anti-ITGB2 Antibody (MEM-148) | FC, IP, WB, BL, FuncS | IgG1 |
| NEUT-1594CQ | Recombinant Hamster Anti-Itgb2 Antibody (2E6) | BL, ICC, IP, FC | IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1884 | Hi-Affi™ Recombinant Rabbit Anti-ITGB2 Monoclonal Antibody (DS1884AB) | IP, WB | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0203CQ-S(P) | Mouse Anti-ITGB2 Recombinant Antibody (clone 60.3); scFv Fragment | ELISA, WB, Block | Mouse scFv |
| FAMAB-0204CQ-S(P) | Human Anti-ITGB2 Recombinant Antibody (clone h60.3); scFv Fragment | ELISA, WB, Block | Human scFv |
| HPAB-0801-CN-S(P) | Recombinant Mouse Anti-ITGB2 Antibody scFv Fragment (CBCNC1) | ELISA, IHC | Mouse scFv |
| HPAB-1376WJ-S(P) | Human Anti-ITGB2 Recombinant Antibody; scFv Fragment (clone huH52) | ELISA, WB | Human scFv |
| HPAB-1569WJ-S(P) | Mouse Anti-ITGB2 Recombinant Antibody; scFv Fragment (clone 1B4) | ELISA, WB, IF | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0801-CN-F(E) | Recombinant Mouse Anti-ITGB2 Antibody Fab Fragment (CBCNC1) | ELISA, IHC | Mouse Fab |
| HPAB-1769-FY-S(P) | Human Anti-ITGB2 Recombinant Antibody (clone D2-57); Fab Fragment | ELISA | Human Fab |
| HPAB-1770-FY-S(P) | Human Anti-ITGB2 Recombinant Antibody (clone DX-2001); Fab Fragment | ELISA | Human Fab |
| HPAB-1771-FY-S(P) | Human Anti-ITGB2 Recombinant Antibody (clone C1-54); Fab Fragment | ELISA | Human Fab |
| HPAB-1207WJ-F(E) | Human Anti-ITGB2 Recombinant Antibody (clone pxCD18-7T3); Fab Fragment | ELISA | Human Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-044 | Afuco™ Anti-ITGB2 ADCC Recombinant Antibody (Rovelizumab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FN-085CQ | Recombinant Rat Anti-ITGB2 Antibody (C71/16) | IHC-Fr, FC, IP, FuncS | Rat IgG2a |
| HPAB-1769-FY | Human Anti-ITGB2 Recombinant Antibody (clone D2-57) | ELISA | Human IgG |
| HPAB-1770-FY | Human Anti-ITGB2 Recombinant Antibody (clone DX-2001) | ELISA | Human IgG |
| HPAB-1771-FY | Human Anti-ITGB2 Recombinant Antibody (clone C1-54) | ELISA | Human IgG |
| HPAB-1292WJ | Rat Anti-ITGB2 Recombinant Antibody (clone YFC51.1) | ELISA, FC | Rat IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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