Human Anti-ITGB2 Recombinant Antibody (clone h60.3) (CAT#: FAMAB-0204CQ)

Antibody clone h60.3 is specific to CD18. Clone 60.3 binds to the CD18 component of the beta 2 integrin family of adhesion molecules. The mAb has potential clinical application in blocking the neutrophil-mediated organ damage which occurs following a myocardial infarct or hemorrhagic shock.

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FACS

Figure 1 Competitive binding of murine, chimeric and humanized 60.3 variants to HL-60 cells.

Figure 1 Competitive binding of murine, chimeric and humanized 60.3 variants to HL-60 cells.

The amount of FITC m60.3 binding to HL-60 cells was determined by FACS analysis.


Specifications

  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • Humanized IgG1, κ
  • Specificity
  • Human ITGB2
  • Species Reactivity
  • Human
  • Clone
  • h60.3
  • Applications
  • ELISA, WB, Block
  • Related Disease
  • Leukocyte adhesion deficiency (LAD)

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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CAT Product Name Application Type
NABG-099 Recombinant Anti-Human ITGB2 VHH Single Domain Antibody ELISA, IHC, FC, FuncS Llama VHH

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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