Rabbit Anti-ITGB3 Antibody (VS-0924-YC55) - Cancer Stem Cell Marker (CAT#: VS-0924-YC55)
Introducing the Anti-ITGB3 Antibody (VS-0924-YC55), specifically designed to target the human ITGB3 protein, a recognized marker for cancer stem cells (CSCs). This antibody is ideal for detecting ITGB3 in CSC tissues or cells through Immunohistochemistry, with a recommended dilution range of 1:200 to 1:500.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27852/281_B9_2_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27852/281_B9_2_selected.jpg
Figure 2 IHC staining of human bone marrow
(Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in megakaryocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27852/ihc_selected.jpg
(Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in megakaryocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27852/ihc_selected.jpg
Figure 3 Bone marrow
(Hematopoietic cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27852/64673_B_4_4.jpg
(Hematopoietic cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27852/64673_B_4_4.jpg
Figure 4 RNA cell line category: Cell line enhanced (EFO-21, HEL, RPTEC TERT1, U-87 MG, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000259207-ITGB3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000259207-ITGB3
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human ITGB3
- Species Reactivity
- Human
- Applications
- IHC
Product Property
- Clonality
- Polyclonal
- Purification
- Affinity purified using the PrEST antigen as affinity ligand
- Buffer
- PBS, pH 7.2, with 40% glycerol
- Preservative
- 0.02% Sodium azide
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunohistochemistry (IHC): 1/200-1/500
Target
- Alternative Names
- CD61; GP3A; GPIIIa
- Gene ID
- 3690
- UniProt ID
- P05106
- Long Name
- Integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
- Cellular Localization
- Cell junction, Cell membrane, Cell projection, Membrane
Recommended Products
Isotype Control
Secondary Antibody
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| NAB-785-sdAb | Recombinant Anti-human ITGB3 VHH Single Domain Antibody | FA, FC, ICC, ELISA | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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