Human Anti-IVIG Recombinant Antibody (clone GGb-04) (CAT#: FAMAB-0033JF)
GGb-04 is a recombinant monoclonal antibody that specially binds to human IVIG. This human anti-IVIG antibody GGb-04 can be poteincially used in the treatment study of autoimmune thrombocytopenic purpura.
Specific Inquiry
FC
Figure 1 IVIG Induces Selective In Vivo Overexpression of FcγRIIB on Infiltrating Macrophages in Wt Mice but Not in op/op Mice.
The percentages of cells in quadrants are indicated.
Bruhns, P., Samuelsson, A., Pollard, J. W., & Ravetch, J. V. (2003). Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease. Immunity, 18(4), 573-581.
IHC
Figure 2 Hematoxylin-eosin staining of op/op ankle sections of K/BxN serum-treated or IVIGK/BxN serum-treated mice at day 6.
Severe synovitis and massive infiltration of neutrophils is present in both conditions.
Bruhns, P., Samuelsson, A., Pollard, J. W., & Ravetch, J. V. (2003). Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease. Immunity, 18(4), 573-581.
Specifications
- Host Species
- Human
- Derivation
- Human phage display Fab library
- Type
- Human IgG
- Specificity
- Human IVIG
- Species Reactivity
- Human
- Clone
- GGb-04
- Applications
- ELISA, IHC
- Related Disease
- Autoimmune thrombocytopenic purpura
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The IVIG antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Immunohistochemistry.
Target
- Alternative Names
- Intravenous immunoglobulins; IVIG
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone GGb-04"
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-592 | Recombinant Anti-IVIG Antibody | ELISA, IP, FuncS | IgG |
| MHH-592 | Recombinant Human Anti-IVIG Antibody | RIA, WB, FuncS | IgG |
| FAMAB-0032JF | Human Anti-IVIG Recombinant Antibody (clone LO10) | WB, ELISA, IHC, Inhib | Human IgG |
| FAMAB-0034JF | Human Anti-IVIG Recombinant Antibody (clone NK07) | ELISA, IHC, Inhib | Human IgG |
| VS-0423-CJ16 | Human Anti-IVIG Recombinant Antibody (clone mg30b) | ELISA | Human IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-592-F(E) | Recombinant Anti-IVIG Antibody Fab Fragment | WB, ELISA, FuncS | Fab |
| MHH-592-F(E) | Recombinant Human Anti-IVIG Antibody Fab Fragment | ELISA, WB, Neut, FuncS | Fab |
| FAMAB-0032JF-F(E) | Human Anti-IVIG Recombinant Antibody (clone LO10); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| FAMAB-0033JF-F(E) | Human Anti-IVIG Recombinant Antibody (clone GGb-04); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| FAMAB-0034JF-F(E) | Human Anti-IVIG Recombinant Antibody (clone NK07); Fab Fragment | WB, ELISA, FuncS | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-592-S(P) | Recombinant Anti-IVIG Antibody scFv Fragment | IF, Neut, FuncS | scFv |
| MHH-592-S(P) | Recombinant Human Anti-IVIG Antibody scFv Fragment | ELISA, IP, FuncS | scFv |
| FAMAB-0032JF-S(P) | Human Anti-IVIG Recombinant Antibody (clone LO10); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| FAMAB-0033JF-S(P) | Human Anti-IVIG Recombinant Antibody (clone GGb-04); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| FAMAB-0034JF-S(P) | Human Anti-IVIG Recombinant Antibody (clone NK07); scFv Fragment | WB, ELISA, FuncS | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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