Human Anti-IVIG Recombinant Antibody (clone NK07) (CAT#: FAMAB-0034JF)
Recombinant monoclonal antibody NK07 can specially bind to human IVIG. This human anti-IVIG antibody NK07 can be poteincially used in the treatment studies of patients with autoimmune thrombocytopenic purpura.
Specific Inquiry
ELISA
Figure 1 Anti-M1 antibodies in IVIG.
The absorbance of the blank and the positive control at 415 nm was 0.105 and 1.30, respectively.
Basma, H., Norrby-Teglund, A., McGeer, A., Low, D. E., El-Ahmedy, O., Dale, J. B., ... & Kotb, M. (1998). Opsonic antibodies to the surface M protein of group A streptococci in pooled normal immunoglobulins (IVIG): potential impact on the clinical efficacy of IVIG therapy for severe invasive group A streptococcal infections. Infection and immunity, 66(5), 2279-2283.
Inhib
Figure 2 Inhibition of pemphigus vulgaris (PV)-IgG binding to recombinant.desmoglein-3 (r.desmoglein-3) by IVIG.
The data are presented in OD at 405 nm.
Mimouni, D., Blank, M., Ashkenazi, L., Milner, Y., Frusic‐Zlotkin, M., Anhalt, G. J., ... & Shoenfeld, Y. (2005). Protective effect of intravenous immunoglobulin (IVIG) in an experimental model of pemphigus vulgaris. Clinical & Experimental Immunology, 142(3), 426-432.
IHC
Figure 3 IgG deposition in the pemphigus vulgaris PV-IgG injected mice treated with IVIG.
Immunohistochemistry slides demonstrating intercellular binding.
Mimouni, D., Blank, M., Ashkenazi, L., Milner, Y., Frusic‐Zlotkin, M., Anhalt, G. J., ... & Shoenfeld, Y. (2005). Protective effect of intravenous immunoglobulin (IVIG) in an experimental model of pemphigus vulgaris. Clinical & Experimental Immunology, 142(3), 426-432.
Specifications
- Host Species
- Human
- Derivation
- Human phage display Fab library
- Type
- Human IgG
- Specificity
- Human IVIG
- Species Reactivity
- Human
- Clone
- NK07
- Applications
- ELISA, IHC, Inhib
- Related Disease
- Autoimmune thrombocytopenic purpura
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The IVIG antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Immunohistochemistry, Inhibition.
Target
- Alternative Names
- Intravenous immunoglobulins; IVIG
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-592 | Recombinant Anti-IVIG Antibody | ELISA, IP, FuncS | IgG |
| MHH-592 | Recombinant Human Anti-IVIG Antibody | RIA, WB, FuncS | IgG |
| FAMAB-0032JF | Human Anti-IVIG Recombinant Antibody (clone LO10) | WB, ELISA, IHC, Inhib | Human IgG |
| FAMAB-0033JF | Human Anti-IVIG Recombinant Antibody (clone GGb-04) | ELISA, IHC | Human IgG |
| VS-0423-CJ16 | Human Anti-IVIG Recombinant Antibody (clone mg30b) | ELISA | Human IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-592-F(E) | Recombinant Anti-IVIG Antibody Fab Fragment | WB, ELISA, FuncS | Fab |
| MHH-592-F(E) | Recombinant Human Anti-IVIG Antibody Fab Fragment | ELISA, WB, Neut, FuncS | Fab |
| FAMAB-0032JF-F(E) | Human Anti-IVIG Recombinant Antibody (clone LO10); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| FAMAB-0033JF-F(E) | Human Anti-IVIG Recombinant Antibody (clone GGb-04); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| FAMAB-0034JF-F(E) | Human Anti-IVIG Recombinant Antibody (clone NK07); Fab Fragment | WB, ELISA, FuncS | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-592-S(P) | Recombinant Anti-IVIG Antibody scFv Fragment | IF, Neut, FuncS | scFv |
| MHH-592-S(P) | Recombinant Human Anti-IVIG Antibody scFv Fragment | ELISA, IP, FuncS | scFv |
| FAMAB-0032JF-S(P) | Human Anti-IVIG Recombinant Antibody (clone LO10); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| FAMAB-0033JF-S(P) | Human Anti-IVIG Recombinant Antibody (clone GGb-04); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| FAMAB-0034JF-S(P) | Human Anti-IVIG Recombinant Antibody (clone NK07); scFv Fragment | WB, ELISA, FuncS | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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