Rabbit Anti-KIF3A Recombinant Antibody (clone R03-8K9)
CAT#: VS3-XY3407
The rabbit recombinant antibody specifically binds to human KIF3A (Kinesin family member 3A), which plays a role in centriole cohesion and subdistal appendage organization and function. It also has cross-reactivity against mouse and rat KIF3A. It has been detected using Western Blot and Immunoprecipitation.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37085/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human cerebellum
Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37085/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37085/72113_B_9_5.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37085/72113_A_6_6.jpg
RNA Expression
Figure 5 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000131437-KIF3A
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat KIF3A
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R03-8K9
- Applications
- WB, IP
- Related Disease
- Endocrine-Cerebroosteodysplasia; Meckel Syndrome, Type 1
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IP: 1/20
Target
- Alternative Names
- FLA10; KLP-20
- Gene ID
- 11127
- UniProt ID
- Q9Y496
- Long Name
- Kinesin family member 3A
- Cellular Localization
- Cytoplasm, Cytoskeleton, Cell projection, cilium
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (Q9Y496)
Modification sites at neXtProt (NX_Q9Y496)
Glycosylation from GlyGen (Q9Y496) 2 sites, 1 O-linked glycan (2 sites)
- Protein Refseq
- XP_016864485.1; XP_006714589.1
- Function
- Microtubule-based anterograde translocator for membranous organelles.
Plus end-directed microtubule sliding activity in vitro.
Plays a role in primary cilia formation.
Plays a role in centriole cohesion and subdistal appendage organization and function.
Regulates the formation of the subdistal appendage via recruitment of DCTN1 to the centriole.
Also required for ciliary basal feet formation and microtubule anchoring to mother centriole.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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- Product Name
Recommended Dilution Buffer
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Secondary Antibody
- CAT
- Product Name
See other products for "KIF3A"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0962CT | Recombinant Mouse anti-Rat KIF3A Monoclonal antibody (L3.5) | BL, ICC, IF, WB | |
| MRO-1995-CN | Rabbit Anti-KIF3A Polyclonal Antibody (MRO-1995-CN) | WB, IHC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1625CQ | Recombinant Mouse Anti-KIF3A Antibody (NEUT-1625CQ) | BL, ICC, IF, WB | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1939 | Hi-Affi™ Recombinant Rabbit Anti-KIF3A Monoclonal Antibody (DS1939AB) | WB, IP, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3773 | Anti-KIF3A Immunohistochemistry Kit | IHC | |
| VS-0525-XY3774 | Anti-Mouse KIF3A Immunohistochemistry Kit | IHC |
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