Rabbit Anti-KLKB1 Recombinant Antibody (clone R04-6H8) (CAT#: VS3-XY3409)
This is a recombinant rabbit antibody targeting the KLKB1 (Kallikrein B1), which participates in the surface-dependent activation of blood coagulation. It specifically recognizes and binds to human and mouse KLKB1. It has been reported for use in Western Blot, Immunohistochemistry-Paraffin and Immunoprecipitation. The recommended dilutions of Western blot, Immunohistochemistry-Paraffin and Immunoprecipitation is 1/500-1/1000, 1/50-1/100 and 1/20, respectively.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (NTERA-2, SCLC-21H, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164344-KLKB1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164344-KLKB1
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Rat KLKB1
- Species Reactivity
- Human, Rat
- Clone
- R04-6H8
- Applications
- WB, IHC-P, IP
- Related Disease
- Prekallikrein Deficiency; Congenital Prekallikrein Deficiency
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IP: 1/20
Target
- Alternative Names
- PKK; PPK; KLK3; PKKD
- Gene ID
- 3818
- UniProt ID
- P03952
- Long Name
- Kallikrein B1
- Cellular Localization
- Secreted
- Post Translation Modifications
- Glycosylation at Asn127, Asn164, Asn254, Asn308, Asn316, Asn396, Asn453, and Asn494 (NX_P03952 [NX_P03952-1])
Modification sites at PhosphoSitePlus (P03952)
Glycosylation from GlyConnect KLKB1_HUMAN (714)
Glycosylation from GlyGen (P03952) 9 sites, 23 N-linked glycans (8 sites), 1 O-linked glycan (1 site)
- Protein Refseq
- XP_016863670.1
- Function
- The enzyme cleaves Lys-Arg and Arg-Ser bonds.
It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface.
It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "KLKB1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1983z | Mouse Anti-KLKB1 Recombinant Antibody (clone 32C8) | WB | Mouse IgG1 |
| PABL-257 | Human Anti-KLKB1 Recombinant Antibody (PABL-257) | Block, FuncS | Human IgG |
| MOB-1612CT | Recombinant Mouse anti-Human KLKB1 Monoclonal antibody (24H22) | ELISA, IHC-P, Inhib, WB | |
| HPAB-1573-FY | Human Anti-KLKB1 Recombinant Antibody (HPAB-1573-FY) | Inhib | Human IgG |
| ZG-0788J | Rabbit Anti-KLKB1 Recombinant Antibody (clone 9F6) | ELISA, IHC | Rabbit IgG |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-472CL | Human Anti-KLKB1 Recombinant Antibody (TAB-472CL) | Inhib, FuncS | Human IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-257 | Human Anti-KLKB1 Recombinant Antibody; scFv Fragment (PSBL-257) | Block, FuncS | Human scFv |
| HPAB-1573-FY-F(E) | Human Anti-KLKB1 Recombinant Antibody; Fab Fragment (HPAB-1573-FY-F(E)) | Inhib | Human Fab |
| HPAB-1574-FY-F(E) | Human Anti-KLKB1 Recombinant Antibody; Fab Fragment (HPAB-1574-FY-F(E)) | ELISA | Human Fab |
| HPAB-1575-FY-F(E) | Human Anti-KLKB1 Recombinant Antibody; Fab Fragment (HPAB-1575-FY-F(E)) | ELISA | Human Fab |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-257 | Human Anti-KLKB1 Recombinant Antibody; Fab Fragment (PFBL-257) | Block, FuncS | Human Fab |
| HPAB-1573-FY-S(P) | Human Anti-KLKB1 Recombinant Antibody; scFv Fragment (HPAB-1573-FY-S(P)) | Inhib | Human scFv |
| HPAB-1574-FY-S(P) | Human Anti-KLKB1 Recombinant Antibody; scFv Fragment (HPAB-1574-FY-S(P)) | ELISA | Human scFv |
| HPAB-1575-FY-S(P) | Human Anti-KLKB1 Recombinant Antibody; scFv Fragment (HPAB-1575-FY-S(P)) | ELISA | Human scFv |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1655CQ | Recombinant Mouse Anti-KLKB1 Antibody (13G11) | ELISA, Inhib, WB | IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1965 | Hi-Affi™ Recombinant Rabbit Anti-KLKB1 Monoclonal Antibody (DS1965AB) | WB, IHC, IP | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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