Mouse Anti-KRT10 Recombinant Antibody (clone ABT-CK10) (CAT#: VS3-CJ630)
This product is a mouse antibody that recognizes human KRT10.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 High expression in skin 1
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12014/ihc_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12014/ihc_selected.jpg
Figure 2 Low expression in colon
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12014/143516_A_8_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12014/143516_A_8_3_val_selected.jpg
Figure 3 Skin
(Cells in corneal layer Staining: Medium Intensity: Moderate Quantity:>75% Cells in granular layer Staining: Medium Intensity: Moderate Quantity:>75% Cells in spinous layer Staining: Medium Intensity: Moderate Quantity:>75% Eccrine glands Staining: Medium Intensity: Moderate Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/132/2531_B_8_1.jpg
(Cells in corneal layer Staining: Medium Intensity: Moderate Quantity:>75% Cells in granular layer Staining: Medium Intensity: Moderate Quantity:>75% Cells in spinous layer Staining: Medium Intensity: Moderate Quantity:>75% Eccrine glands Staining: Medium Intensity: Moderate Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/132/2531_B_8_1.jpg
Figure 4 RNA cell line category: Cell line enriched (hTCEpi)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186395-KRT10
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186395-KRT10
Specifications
- Immunogen
- Synthesized peptide derived from human Cytokeratin 10
- Host Species
- Mouse
- Type
- Mouse IgG3, κ
- Specificity
- Human KRT10
- Species Reactivity
- Human
- Clone
- ABT-CK10
- Applications
- IHC-P
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity Chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 0.5% BSA, PBS.
- Preservative
- 0.02% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Immunohistochemistry-Parraffin (1:100-1:500).
Target
- Alternative Names
- BIE; EHK; K10; KPP; BCIE; CK10
- Gene ID
- 3858
- UniProt ID
- P13645
- Sequence Similarities
- Belongs to the intermediate filament family.
- Cellular Localization
- Intermediate filament, Keratin, Secreted
- Protein Refseq
- NP_000412.3
- Function
- Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity).
Involved in the maintenance of cell layer development and keratin filament bundles in suprabasal cells of the epithelium (By similarity).
(Microbial infection) Acts as a mediator of S.aureus adherence to desquamated nasal epithelial cells via clfB, and hence may play a role in nasal colonization.
(Microbial infection) Binds S.pneumoniae PsrP, mediating adherence of the bacteria to lung cell lines. Reduction of levels of KRT10 keratin decrease adherence, overexpression increases adherence. Neither protein has to be glycosylated for the interaction to occur.
Recommended Products
Isotype Control
Secondary Antibody
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "KRT10"
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1975 | Hi-Affi™ Recombinant Rabbit Anti-KRT10 Monoclonal Antibody (DS1975AB) | ICC, IHC-P, IP, WB | IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0434-CN | Recombinant Rabbit Anti-KRT10 Monoclonal Antibody (CBACN-174) | WB, IF, IHC | Rabbit IgG |
| VS1-YJ41 | Mouse Anti-KRT10 Recombinant Antibody (clone AE20) | IHC-P, IHC-Fr, WB | Mouse IgG |
| VS3-FY803 | Recombinant Mouse Anti-KRT10 Antibody (clone 1E4G3) | ELISA, WB, FC | Mouse IgG1 |
| VS3-FY804 | Recombinant Mouse Anti-KRT10 Antibody (clone 7A5A6) | ELISA, WB, IHC, ICC, FC | Mouse IgG1 |
| VS3-FY805 | Recombinant Mouse Anti-KRT10 Antibody (clone 4E5-10C9-7B1) | IHC-P | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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