Rabbit Anti-KRT10 Recombinant Antibody (VS13-YC630)
CAT#: VS13-YC630
The Rabbit Anti-KRT10 Recombinant Antibody is specific for human, Hamster, mouse and rat KRT10. KRT10 encodes acidic cytokeratin type I, forming intermediate filaments, affecting epithelial structural integrity. Mutations link to epidermolytic hyperkeratosis, with clustering among type I cytokeratins on chromosome 17q21. The anti-KRT10 antibody can be used for Western blot (1/500-1/1000), Immunohistochemistry (1/50-1/100).
Gene Expression
Normal Tissue
Figure 1 High expression in skin 1
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12014/ihc_selected.jpg
Normal Tissue
Figure 2 Low expression in colon
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12014/143516_A_8_3_val_selected.jpg
Normal Tissue
Figure 3 Skin
Cells in corneal layer Staining: Medium Intensity: Moderate Quantity:>75% Cells in granular layer Staining: Medium Intensity: Moderate Quantity:>75% Cells in spinous layer Staining: Medium Intensity: Moderate Quantity:>75% Eccrine glands Staining: Medium Intensity: Moderate Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/132/2531_B_8_1.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enriched (hTCEpi)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186395-KRT10
❮
❯
Specifications
- Immunogen
- Recombinant human Cytokeratin 10.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Hamster, Mouse and Rat KRT10
- Species Reactivity
- Human, Hamster, Mouse, Rat
- Applications
- WB, IHC-P
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.
- Preservative
- 0.01% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunohistochemistry (IHC): 1/50-1/100
Target
- Alternative Names
- Keratin 10; Keratin 10, Type I; Cytokeratin 10; CK-10; KPP; K10; Keratosis Palmaris Et Plantaris; Keratin, Type I Cytoskeletal 10;
- Gene ID
- 3858
- UniProt ID
- P13645
- Long Name
- Keratin 10
- Sequence Similarities
- Belongs to the intermediate filament family.
- Cellular Localization
- Intermediate filament; Keratin; Secreted
- Protein Refseq
- NP_000412.3
- Function
- Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity).
Involved in the maintenance of cell layer development and keratin filament bundles in suprabasal cells of the epithelium (By similarity).
(Microbial infection) Acts as a mediator of S.aureus adherence to desquamated nasal epithelial cells via clfB, and hence may play a role in nasal colonization.
(Microbial infection) Binds S.pneumoniae PsrP, mediating adherence of the bacteria to lung cell lines. Reduction of levels of KRT10 keratin decrease adherence, overexpression increases adherence. Neither protein has to be glycosylated for the interaction to occur.
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS13-YC630. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "KRT10"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2194MZ | Recombinant Mouse Anti-Human KRT10 Antibody (clone EF-L20) | ICC, IF, IHC-P, WB | Mouse antibody |
| VS3-CJ630 | Mouse Anti-KRT10 Recombinant Antibody (clone ABT-CK10) | IHC-P | Mouse IgG3, κ |
| VS3-CJ631 | Rabbit Anti-KRT10 Recombinant Antibody (VS3-CJ631) | WB, ICC, IF, IHC | Rabbit IgG |
| VS3-FY803 | Recombinant Mouse Anti-KRT10 Antibody (clone 1E4G3) | ELISA, WB, FC | Mouse IgG1 |
| VS3-FY804 | Recombinant Mouse Anti-KRT10 Antibody (clone 7A5A6) | ELISA, WB, IHC, ICC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1975 | Hi-Affi™ Recombinant Rabbit Anti-KRT10 Monoclonal Antibody (DS1975AB) | ICC, IHC-P, IP, WB | IgG |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: ELISA, IP, FC, FuncS, Neut, IF, WB
Application: ELISA, Neut, FuncS
Application: Neut, ELISA, Inhib, ICC, WB
Application: FC, ADCC, CDC, Inhib
-3.jpg)
Application: Neut
Application: ELISA, FC, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
