Rabbit Anti-KRT10 Recombinant Antibody (VS13-YC630) (CAT#: VS13-YC630)

• Immunogen
• Recombinant human Cytokeratin 10.

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human, Hamster, Mouse and Rat KRT10

• Species Reactivity
• Human, Hamster, Mouse, Rat

• Applications
• WB, IHC-P

• Conjugate
• NONE

• Clonality
• Monoclonal

• Purification
• Affinity Chromatography purified

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Buffer
• 50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.

• Preservative
• 0.01% Sodium azide

• Storage
• Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Shipping with ice pack.

• Application Notes
• Western blot (WB): 1/500-1/1000
  Immunohistochemistry (IHC): 1/50-1/100

• Alternative Names
• Keratin 10; Keratin 10, Type I; Cytokeratin 10; CK-10; KPP; K10; Keratosis Palmaris Et Plantaris; Keratin, Type I Cytoskeletal 10;

• Gene ID
• 3858

• UniProt ID
• P13645

• Long Name
• Keratin 10

• Sequence Similarities
• Belongs to the intermediate filament family.

• Cellular Localization
• Intermediate filament; Keratin; Secreted

• Protein Refseq
• NP_000412.3

• Function
• Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity).
  Involved in the maintenance of cell layer development and keratin filament bundles in suprabasal cells of the epithelium (By similarity).
  (Microbial infection) Acts as a mediator of S.aureus adherence to desquamated nasal epithelial cells via clfB, and hence may play a role in nasal colonization.
  (Microbial infection) Binds S.pneumoniae PsrP, mediating adherence of the bacteria to lung cell lines. Reduction of levels of KRT10 keratin decrease adherence, overexpression increases adherence. Neither protein has to be glycosylated for the interaction to occur.

Secondary Antibody

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

• 2ND-061CQ
• Sheep Anti-Rabbit IgG (H&L) Antibody

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

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