Mouse Anti-KRT2 Recombinant Antibody (clone 8A1E1) (CAT#: VS7-0425-WR263)

This product is a mouse IgG2a antibody that binds to human KRT2. The antibody 8A1E1 recognizes specific amino acid domain of human KRT2 (AA: 177-490). It can be used for IHC and ICC assays.

Specific Inquiry
  • Size:

  • Conjugation:

  • Endotoxin:

  • Purity:

  • Formats:

  • Isotype Switching:

  • Fc Engineering:

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Custom Production

We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

Sequences:
Isotype :
Purity :
Endotoxin :
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Other Requirements:
We require custom production
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • Recombinant human KRT2 (AA: 177-490) fragment expressed in E. Coli.
  • Host Species
  • Mouse
  • Type
  • Mouse IgG2a
  • Specificity
  • Human KRT2
  • Species Reactivity
  • Human
  • Clone
  • 8A1E1
  • Molecule Class
  • Type II Keratin Family
  • Applications
  • IHC, ICC
  • Conjugate
  • Unconjugated
  • Related Disease
  • Ichthyosis bullosa of Siemens (IBS)

Product Property

  • Clonality
  • Monoclonal
  • Purity
  • >95% as determined by SDS-PAGE and SEC-HPLC analysis
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • 0.05% sodium azide
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • Western Blot: 1:500 - 1:2000
    Immunohistochemistry-Paraffin: 1:200 - 1:1000
    Immunocytochemistry: 1:500 - 1:2000
    Enzyme-linked Immunosorbent Assay: 1:10000

Target

  • Alternative Names
  • K2e; KRTE; CK-2e; KRT2A; KRT2E
  • Long Name
  • Keratin 2
  • Cellular Localization
  • Cytoplasm; Intermediate filament; Keratin
  • Post Translation Modifications
  • Methylation; Phosphoprotein
  • Function
  • Probably contributes to terminal cornification (PubMed:1380918).; Associated with keratinocyte activation, proliferation and keratinization (PubMed:12598329).; Required for maintenance of corneocytes and keratin filaments in suprabasal keratinocytes in the epidermis of the ear, potentially via moderation of expression and localization of keratins and their partner proteins (By similarity).; Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity).

Recommended Products

Reconstitution Buffer

Recommended Dilution Buffer

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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