Mouse Anti-KRT2 Recombinant Antibody (VS3-FY2757) (CAT#: VS3-FY2757)

• Host Species
• Mouse

• Type
• Mouse IgG

• Specificity
• Keratin 2 of human

• Species Reactivity
• Human

• Applications
• WB, IHC, ICC, FC, ELISA

• Conjugate
• Unconjugated, FITC

• MW
• The molecular weight of the target protein is approximately 65.4 kDa.

• Related Disease
• Ichthyosis Bullosa Of Siemens and Epidermolytic Hyperkeratosis 1

• Clonality
• Monoclonal Antibody

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/2000
  Immunohistochemistry: 1/50-1/200
  Immunocytochemistry: 1/50-1/200
  Flow cytometry: 1/50-1/200
  ELISA: 1/1000-1/10000

• Alternative Names
• Keratin 2; Epithelial Keratin-2e; Keratin-2 Epidermis; Type-II Keratin Kb2; Keratin 2, Type II; Cytokeratin-2e; Keratin-2e; KRT2A

• Gene ID
• 3849

• Sequence Similarities
• Belongs to the intermediate filament family.

• Cellular Localization
• Cytoplasm

• Post Translation Modifications
• Modification sites at PhosphoSitePlus
  Modification sites at neXtProt
  Glycosylation from GlyGen 3 sites, 1 O-linked glycan (3 sites)

• Protein Refseq
• NP_000414.2

• Function
• Associated with keratinocyte activation, proliferation and keratinization (PubMed:12598329).
  Required for maintenance of corneocytes and keratin filaments in suprabasal keratinocytes in the epidermis of the ear, potentially via moderation of expression and localization of keratins and their partner proteins (By similarity).
  Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity).

Secondary Antibody

• 2ND-040CQ
• Goat Anti-Mouse IgG (H&L) Antibody

Isotype Control

• MRO-A1591-YJ
• Mouse IgG Isotype control, Polyclonal

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