Rabbit Anti-LAMC1 Recombinant Antibody (VS13-YC643) (CAT#: VS13-YC643)
The Rabbit Anti-LAMC1 Recombinant Antibody is specific for human LAMC1. LAMC1 encodes laminin gamma 1, essential for heterotrimer laminin assembly, crucial for basement membrane integrity. Transgenic mouse studies suggest its necessity for embryonic viability. The anti-LAMC1 antibody can be used for Immunohistochemistry (1/100-1/200).
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1909/2_H2_1_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1909/2_H2_1_selected.jpg
Figure 2 IHC staining of human placenta
(High expression. RNA expression: 231.7 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1908/6267_A_3_7_val_selected.jpg
(High expression. RNA expression: 231.7 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1908/6267_A_3_7_val_selected.jpg
Figure 3 IHC staining of human tonsil
(Low expression. RNA expression: 12.0 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1908/6267_A_4_8_val_selected.jpg
(Low expression. RNA expression: 12.0 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1908/6267_A_4_8_val_selected.jpg
Figure 4 Cerebral cortex
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranou)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1909/6273_B_8_5.jpg
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranou)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1909/6273_B_8_5.jpg
Figure 5 Colon
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1909/6273_A_7_3.jpg
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1909/6273_A_7_3.jpg
Figure 6 Liver
(Hepatocytes
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1909/6273_A_7_4.jpg
(Hepatocytes
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1909/6273_A_7_4.jpg
Figure 7 Kidney
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1909/6273_A_9_5.jpg
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1909/6273_A_9_5.jpg
Figure 8 Testis
(Pachytene spermatocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Peritubular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1909/6273_A_4_6.jpg
(Pachytene spermatocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Peritubular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1909/6273_A_4_6.jpg
Figure 9 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, HSkMC)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135862-LAMC1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135862-LAMC1
Specifications
- Immunogen
- Recombinant human Laminin gamma 1.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human LAMC1
- Species Reactivity
- Human
- Applications
- IHC-P
- Conjugate
- NONE
- Related Disease
- Lissencephaly and Cutis Laxa, Neonatal, With Marfanoid Phenotype
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.8) containing 50% Glycerol and 0.5% BSA.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Immunohistochemistry (IHC): 1/100-1/200
Target
- Alternative Names
- Laminin Subunit Gamma 1 Laminin, Gamma 1 (Formerly LAMB2); Laminin-10 Subunit Gamma; Laminin-11 Subunit Gamma; Laminin-2 Subunit Gamma; Laminin-3 Subunit Gamma; Laminin-4 Subunit Gamma; Laminin-6 Subunit Gamma; Laminin-7 Subunit Gamma; Laminin-8 Subunit Gamma; Laminin-9 Subunit Gamma; S-Laminin Subunit Gamma; Laminin B2 Chain; S-LAM Gamma; LAMB2
- Gene ID
- 3915
- UniProt ID
- P11047
- Long Name
- Laminin Subunit Gamma 1
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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IgG Antibody Products
Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2372z | Mouse Anti-LAMC1 Recombinant Antibody (clone 42A8) | WB, ELISA, IHC | Mouse IgG1 |
| MOB-1058CT | Recombinant Mouse anti-Rat LAMC1 Monoclonal antibody (E29) | IHC-P | |
| ZG-0667F | Rabbit Anti-LAMC1 Recombinant Antibody (ZG-0667F) | IF, IHC-P, ELISA, RIA | Rabbit IgG |
| ZG-1007F | Rat Anti-LAMC1 Antibody (clone A5) | ICC, IHC-Fr, IF | Rat IgG2a |
| VS3-FY833 | Recombinant Rabbit Anti-LAMC1 Antibody (clone R05-3C5) | WB, IHC-P, IP | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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