Rabbit Anti-LGALS3 Recombinant Antibody (clone R05-8J4) (CAT#: VS3-FY1723)
The R05-8J4 recombinant monoclonal antibody firmly attaches to human LGALS3. It cross-reacts with mouse, rat. It is suitable for use in a variety of assays, including WB, IHC-P. This galectin 3 antibody was used in western blot analysis of galectin 3 in 3T3, Hela lysates.
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WB
Figure 1 Anti-LGALS3 Antibody (VS3-FY1723) in WB.
The Galectin 3 expression in 3T3, Hela lysates were detected using the anti-Galectin 3 by western blot assay.
Specifications
- Immunogen
- Synthetic peptide of human galectin-3
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat LGALS3
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R05-8J4
- Applications
- Western Blot, Immunohistochemistry-Paraffin
- MW
- The calculated weight of the target protein is approximately 26 kDa, while the observed molecular weight stands at 26 kDa.
- Related Disease
- Follicular Adenoma and Papillary Carcinoma
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Target
- Alternative Names
- L31; GAL3; MAC2; CBP35; GALBP; GALIG; LGALS2
- Gene ID
- 3958
- UniProt ID
- P17931
- Cellular Localization
- Cytoplasm, Nucleus, Secreted, Spliceosome
- Protein Refseq
- NP_002297.2
- Function
- Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity).
In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2041 | Hi-Affi™ Recombinant Rabbit Anti-LGALS3 Monoclonal Antibody (DS2041AB) | FC, ICC, WB | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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