Mouse Anti-LGALS3 Recombinant Antibody (VS3-FY2787)
CAT#: VS3-FY2787
The anti-LGALS3 is an impressive mouse recombinant monoclonal antibody that specifically reacts with human epsilon-BP protein. This monoclonal antibody proves valuable in disease research related to Follicular Adenoma and Papillary Carcinoma. It is recommended for detection of target protein by ELISA (1/20000) and Western Blot (1/500-1/2000).
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line SK-MEL-30
Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/76528/2057_C12_5_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm, plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5191/639_D6_1_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IHC staining of human colon
Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5191/ihc_selected.jpg
Normal Tissue
Figure 4 IHC staining of human cerebral cortex
Low expression. RNA expression: 148.1 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3162/8903_B_9_5_val_selected.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3162/8903_A_9_4.jpg
Normal Tissue
Figure 6 Kidney
Collecting ducts
Staining: High
Intensity: Strong
Quantity: 75%-25%
Distal tubules
Staining: High
Intensity: Strong
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3162/8903_A_8_5.jpg
Normal Tissue
Figure 7 Testis
Elongated or late spermatids
Staining: Medium
Intensity: Moderate
Quantity:>75%
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Round or early spermatids
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3162/8903_A_6_6.jpg
Normal Tissue
Figure 8 Skin
Eccrine glands
Staining: High
Intensity: Strong
Quantity:>75%
Fibrohistiocytic cells
Staining: High
Intensity: Strong
Lymphocytes
Staining: High
Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3162/8903_B_7_1.jpg
Normal Tissue
Figure 9 Lymph node
Germinal center cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3162/8903_A_7_8.jpg
RNA Expression
Figure 10 RNA cell line category: Cell line enhanced (ASC TERT1, CAPAN-2, OE19, SK-MEL-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000131981-LGALS3
❮
❯
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human LGALS3
- Species Reactivity
- Human
- Applications
- ELISA, Western Blot-Ce
- Conjugate
- Unconjugated, FITC
- Related Disease
- Follicular Adenoma and Papillary Carcinoma
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- ELISA: 1/20000
Western Blot: 1/500-1/2000
Target
- Alternative Names
- IgE-binding protein; epsilon-BP
- Cellular Localization
- Cytoplasm
Nucleus
Secreted
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (P17931)
Modification sites at neXtProt (NX_P17931)
Glycosylation from GlyGen (P17931) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_002297.2
- Function
- May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration.
Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity).
In the nucleus: acts as a pre-mRNA splicing factor.
Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS3-FY2787. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "LGALS3"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2041 | Hi-Affi™ Recombinant Rabbit Anti-LGALS3 Monoclonal Antibody (DS2041AB) | FC, ICC, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-244YJL | Rabbit Anti-LGALS3 Recombinant Antibody (clone CBL228) | WB, ELISA, FC, ICC, IF, IP | Rabbit IgG |
| MOB-245YJL | Mouse Anti-LGALS3 Recombinant Antibody (clone CBL229) | WB, ELISA, IP | Mouse IgG1 |
| VS3-FY846 | Recombinant Rabbit Anti-LGALS3 Antibody (clone R01-5E1) | WB, IHC-Fr, IHC-P, ICC, IF, IP | Rabbit IgG |
| VS-0923-FY63 | Recombinant Mouse Anti-LGALS3 Antibody (VS-0923-FY63) | ELISA, WB | Mouse IgG1 |
| VS-0824-YJ35 | Human Anti-LGALS3 Recombinant Antibody (clone M3/38) | ELISA, WB, IHC, FC | Chimeric (rat/human) IgG1 kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY171 | AbPlus™ Anti-LGALS3 Magnetic Beads (CBL229) | IP, Protein Purification | |
| VS-0724-YC1497 | AbPlus™ Anti-LGALS3 Magnetic Beads (VS-0724-YC1497) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY40 | Human Anti-LGALS3 (clone P3) scFv-Fc Chimera | BI | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC654 | CytoStream™ Rabbit Anti-LGALS3 Recombinant Antibody (VS13-YC654) | WB, ICC, IF, FC, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3994 | Anti-LGALS3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3995 | Anti-Mouse LGALS3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3997 | Anti-Rat LGALS3 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC204 | Recombinant Anti-LGALS3 Eliminating Antibody, pH-Sensitive (CBL228 var.) | Antigen-Sweeping In Vivo. | Rabbit IgG |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: ELISA, IP, FC, FuncS, Neut, IF, WB
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, IHC, FC, IP, IF, Inhib
-3.jpg)
Application: Neut
Application: ELISA, FuncS, Neut, IF, WB, EM, Inhib, IHC
Application: ELISA, Block, WB, FC, IP
Application: ELISA, Neut
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
