AibGenesis™ Rabbit Anti-LMNB1 Recombinant Antibody (VS-0426-FY889)
CAT#: VS-0426-FY889
VS-0426-FY889 is a high-sensitivity Rabbit IgG targeting Lamin B1, developed through our AI-powered antibody discovery platform. Protein A purified, it is validated for WB, IHC, ICC, IF, ELISA, and IP. This antibody is a gold-standard marker for the nuclear envelope and is essential for studying nuclear architecture, senescence, and aging.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to nuclear membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nuclear membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5269/950_C1_1_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/79757/1894_G3_4_selected.jpg
Subcellular Location and Protein Expression
Figure 4 IHC staining of human colon
Immunohistochemical staining of human colon shows nuclear membrane positivity in glandular and stroma cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 5 IHC staining of human stomach
Immunohistochemical staining of human stomach shows strong nuclear membranous positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5269/155655_A_3_1_selected.jpg
Subcellular Location and Protein Expression
Figure 6 IHC staining of human esophagus
Immunohistochemical staining of human esophagus shows strong nuclear positivity in squamous epithelial cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/79954/171056_B_6_1_selected.jpg
Normal Tissue
Figure 7 Cerebral cortex
Glial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/140330_B_8_5.jpg
Normal Tissue
Figure 8 Kidney
Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/140330_A_7_4.jpg
Normal Tissue
Figure 9 Testis
Cells in seminiferous ducts
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/140330_A_5_6.jpg
Normal Tissue
Figure 10 Lymph node
Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/140330_A_8_8.jpg
RNA Expression
Figure 11 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113368-LMNB1
❮
❯
| Sub Cat | Species Reactivity | Clone | Applications | Size | Conjugation | Endotoxin | Purity | Fc Engineering | |
| VS-0426-FY111 | Human, Mouse, Rat | AibG-Rb-LM111 | WB, IHC, ICC, IF, ELISA, IP | ||||||
| VS-0426-FY112 | Human, Mouse, Rat | AibG-Rb-LM112 | WB, IHC, ICC, IF, FC, IP |
More Infomation
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- LMNB1
- Conjugate
- Unconjugated, Biotin and FITC are available.
- Related Disease
- Autosomal Dominant Leukodystrophy
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Format
- Liquid
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Target
- Alternative Names
- LMNB1; LMN2; LMNB; Lamin-B1
- Gene ID
- 4001
- UniProt ID
- P20700
- Long Name
- Lamin B1
- Sequence Similarities
- Belongs to the intermediate filament family.
- Cellular Localization
- Intermediate filament, Nucleus
- Post Translation Modifications
- B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations.
- Protein Refseq
- NP_005564.1
- Function
- Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0426-FY889. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "LMNB1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1818z | Mouse Anti-LMNB1 Recombinant Antibody (clone 19G6) | ELISA, IHC, WB | Mouse IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2469CT | Recombinant Mouse anti-Chicken LMNB1 Monoclonal antibody (T70) | WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2068 | Hi-Affi™ Recombinant Rabbit Anti-LMNB1 Monoclonal Antibody (DS2068AB) | WB, IHC, IP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC3725 | PE-A*02:02/Human LMNB1 (ELRELNDRL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC3726 | PE-A*02:01/Human LMNB1 (ELRELNDRL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC3727 | PE-A*68:02/Human LMNB1 (ELRELNDRL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC3728 | PE-A*02:01/Human LMNB1 (RLAVYIDKV) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC3729 | PE-A*68:02/Human LMNB1 (RLAVYIDKV) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0913-CN | Recombinant Rabbit Anti-LMNB1 Monoclonal Antibody (CBACN-342) | WB, IF, IHC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0914-CN | Recombinant Rabbit Anti-LMNB1 Monoclonal Antibody (JM099-03) | WB, IHC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-2006-CN | Rabbit Anti-LMNB1 Polyclonal Antibody (MRO-2006-CN) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0075-FY | Rabbit Anti-LMNB1 Recombinant Antibody (clone AFY0046) | ICC, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY176 | AbPlus™ Anti-LMNB1 Magnetic Beads (CBACN-342) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4053 | Anti-LMNB1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4054 | Anti-Mouse LMNB1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4055 | Anti-Rat LMNB1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0726-YC2227 | Human LMNB1 Quick ELISA Kit (VS-0726-YC2227) | ELISA |
See Our Custom Production in Action
Popular Products
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
![Llama Anti-human LC-kappa VHH Single Domain Antibody [Biotin]](https://img.creativebiolabs.net/productimages/COA-NABG-118-1-3.png)
Application: ELISA, WB, BLI, SPR
Application: WB, IHC, FC, Cyt, ELISA
Application: ELISA, Neut, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
