Recombinant Human Anti-LPS Antibody (S20) (CAT#: FAMAB-0104-CN)

Human mAb S20 binds only to P. aeruginosa 06ad LPS O-side-chain PS and not to LPS O-side-chain PSs from other strains. S20 is effective at fixing complement to the bacterial surface.


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ELISA

Figure 1 Blocking of the binding of human anti-LPS MAb S20 to solid-phase P. aeruginosa strain 06ad LPS O-side-chain PS in an ELISA.

Figure 1 Blocking of the binding of human anti-LPS MAb S20 to solid-phase P. aeruginosa strain 06ad LPS O-side-chain PS in an ELISA.

The x axis shows micrograms of 06ad PS or control PS per milliliter added to each reaction tube. The y axis depicts the percent reduction of absorbance obtained with the PS inhibitor.

Hemachandra, S., Kamboj, K., Copfer, J., Pier, G., Green, L. L., & Schreiber, J. R. (2001). Human monoclonal antibodies against Pseudomonas aeruginosa lipopolysaccharide derived from transgenic mice containing megabase human immunoglobulin loci are opsonic and protective against fatal pseudomonas sepsis. Infection and immunity, 69(4), 2223-2229.


Specifications

  • Immunogen
  • Heat-killed 06ad P. aeruginosa
  • Host Species
  • Human
  • Type
  • Human IgG2
  • Specificity
  • Pseudomonas aeruginosa LPS
  • Species Reactivity
  • Pseudomonas aeruginosa
  • Clone
  • S20
  • Applications
  • Used for immunoassay techniques such as: Enzyme Linked Immunoabsorbent Assay; Flow Cytometry; Blocking

Product Property

  • Storage
  • Store at -20°C for long-term storage. Avoid freeze/thaw cycles.

Target

  • Alternative Names
  • LPS

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Single-domain Antibody

CAT Product Name Application Type
NABL-060 Recombinant Anti-V. cholerae O1 LPS VHH Single Domain Antibody WB, ELISA, IP, FuncS Llama VHH

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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