Human mAb S20 binds only to P. aeruginosa 06ad LPS O-side-chain PS and not to LPS O-side-chain PSs from other strains. S20 is effective at fixing complement to the bacterial surface.
Figure 1 Blocking of the binding of human anti-LPS MAb S20 to solid-phase P. aeruginosa strain 06ad LPS O-side-chain PS in an ELISA.
The x axis shows micrograms of 06ad PS or control PS per milliliter added to each reaction tube. The y axis depicts the percent reduction of absorbance obtained with the PS inhibitor.
Hemachandra, S., Kamboj, K., Copfer, J., Pier, G., Green, L. L., & Schreiber, J. R. (2001). Human monoclonal antibodies against Pseudomonas aeruginosa lipopolysaccharide derived from transgenic mice containing megabase human immunoglobulin loci are opsonic and protective against fatal pseudomonas sepsis. Infection and immunity, 69(4), 2223-2229.
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CAT | Product Name | Application | Type |
---|---|---|---|
NABL-060 | Recombinant Anti-V. cholerae O1 LPS VHH Single Domain Antibody | WB, ELISA, IP, FuncS | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
PABL-027 | Recombinant Mouse Anti-C. trachomatis LPS Antibody (SAG506-01) | WB, ELISA, FuncS | IgG |
PABL-265 | Recombinant Mouse Anti-LPS Antibody (S25-2) | WB, IHC, FuncS | IgG |
PABW-013 | Mouse Anti-LPS Recombinant Antibody (clone S45-18) | WB, ELISA | Mouse IgG |
PABZ-112 | Recombinant Mouse Anti-S. flexneri Lipopolysaccharide Antibody (SYA/J6) | WB, FuncS | IgG |
HPAB-0235-FY | Recombinant Human Anti-LPS Antibody (1774) | WB, E | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-265 | Recombinant Mouse Anti-LPS Antibody scFv Fragment (S25-2) | WB, IHC, FuncS | scFv |
HPAB-0235-FY-S(P) | Recombinant Human Anti-LPS Antibody scFv Fragment (1774) | WB, E | Human scFv |
FAMAB-0085WJ-S(P) | Human Anti-LPS Recombinant Antibody (clone H4C5); scFv Fragment | FC, ELISA | Human scFv |
FAMAB-0086WJ-S(P) | Human Anti-LPS Recombinant Antibody (clone 216); scFv Fragment | FC, ELISA | Human scFv |
FAMAB-0087WJ-S(P) | Human Anti-LPS Recombinant Antibody (clone HR78); scFv Fragment | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0207-YC-F(E) | Recombinant Human Anti-LPS Antibody Fab Fragment (sc12) | ELISA, IF, WB | Human Fab |
FAMAB-0244-CN-F(E) | Recombinant Chimeric (Mouse/Human) Anti-LPS Antibody Fab Fragment (CK3) | WB, ELISA | Chimeric (mouse/human) Fab |
FAMAB-0245-CN-F(E) | Recombinant Mouse Anti-LPS Antibody Fab Fragment (BML-5D11) | ELISA | Mouse Fab |
FAMAB-0246-CN-F(E) | Recombinant Mouse Anti-LPS Antibody Fab Fragment (BML-18F8) | ELISA | Mouse Fab |
FAMAB-0247-CN-F(E) | Recombinant Mouse Anti-LPS Antibody Fab Fragment (BP1-2E7) | ELISA | Mouse Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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