Human Anti-LPS Recombinant Antibody (clone 216) (CAT#: FAMAB-0086WJ)

This product is a human monoclonal antibody. This antibody can bind to the lipid A domain of bacterial LPS, which also react with the following Ag: the i Ag present on cord RBC, a ligand on human B lymphocytes, and to certain autoantigens.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Datasheet
  • MSDS
  • COA
FC

Figure 1 Representative contour plots depicting the spectrum of mAb 216 binding.

Figure 1 Representative contour plots depicting the spectrum of mAb 216 binding.

Bone marrow specimens were stained with biotin-labeledcontrol IgM (mAb MS2B6) or mAb 216 and CD 19, and analyzed on a Flasher II (an enhanced Becton Dickinson cytomation MoFlo). Bone marrowsample #8 (top) illustrates homogeneous high binding to mAb 216 and sample #12 (bottom) shows a continuum in 216 binding.

Bieber, M. M., Twist, C. J., Bhat, N. M., & Teng, N. N. (2007). Effects of human monoclonal antibody 216 on B‐progenitor acute lymphoblastic leukemia in vitro. Pediatric blood & cancer, 48(4), 380-386.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgM
  • Specificity
  • Lipid A domain of bacterial LPS
  • Clone
  • 216
  • Applications
  • FC, ELISA

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Lipopolysaccarides; LPS

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 216"

See other products for "LPS"

Single-domain Antibody

CAT Product Name Application Type
NABL-060 Recombinant Anti-V. cholerae O1 LPS VHH Single Domain Antibody WB, ELISA, IP, FuncS Llama VHH

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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