Human Anti-LPS Recombinant Antibody (clone 216) (CAT#: FAMAB-0086WJ)

This product is a human monoclonal antibody. This antibody can bind to the lipid A domain of bacterial LPS, which also react with the following Ag: the i Ag present on cord RBC, a ligand on human B lymphocytes, and to certain autoantigens.

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  • Published Data
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FC

Figure 1 Representative contour plots depicting the spectrum of mAb 216 binding.

Figure 1 Representative contour plots depicting the spectrum of mAb 216 binding.

Bone marrow specimens were stained with biotin-labeledcontrol IgM (mAb MS2B6) or mAb 216 and CD 19, and analyzed on a Flasher II (an enhanced Becton Dickinson cytomation MoFlo). Bone marrowsample #8 (top) illustrates homogeneous high binding to mAb 216 and sample #12 (bottom) shows a continuum in 216 binding.

Bieber, M. M., Twist, C. J., Bhat, N. M., & Teng, N. N. (2007). Effects of human monoclonal antibody 216 on B‐progenitor acute lymphoblastic leukemia in vitro. Pediatric blood & cancer, 48(4), 380-386.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgM
  • Specificity
  • Lipid A domain of bacterial LPS
  • Clone
  • 216
  • Applications
  • FC, ELISA

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Lipopolysaccarides; LPS

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Exceptional Endotoxin Detection
The human anti-LPS recombinant antibody from Creative Biolabs shows exceptional sensitivity in detecting endotoxins, greatly enhancing research accuracy in bacterial infection studies. Its performance is notably superior to other similar products.

Superior Performance in Sepsis Research
Utilizing Creative Biolabs' human anti-LPS recombinant antibody in sepsis research provides superior performance, enhancing the sensitivity of assays. This product consistently delivers reliable results, outperforming other commercially available antibodies.

Reliable Results in Inflammatory Response Studies
The human anti-LPS recombinant antibody from Creative Biolabs provides reliable results in inflammatory response studies. Its superior detection capabilities streamline experimental workflows.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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