Rabbit Anti-LTF Recombinant Antibody (clone R03-8H9) (CAT#: VS3-XY3422)
This product is a recombinant rabbit antibody binding to LTF (Lactotransferrin). This antibody specifically reacts with human LTF. It has been detected by Western Blot, Immunohistochemistry-Paraffin and Immunoprecipitation. The recommended dilutions of Western blot, Immunohistochemistry-Paraffin and Immunoprecipitation is 1/500-1/1000, 1/50-1/100 and 1/20, respectively.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Group enriched (RPMI-8226, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000012223-LTF
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000012223-LTF
Figure 1 RNA cell line category: Group enriched (RPMI-8226, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000012223-LTF
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000012223-LTF
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human LTF
- Species Reactivity
- Human
- Clone
- R03-8H9
- Applications
- WB, IHC-P, IP
- Related Disease
- Mastitis; Keratoconjunctivitis Sicca
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IP: 1/20
Target
- Alternative Names
- LF; HLF2; GIG12; HEL110
- Gene ID
- 4057
- UniProt ID
- P02788
- Long Name
- Lactotransferrin
- Cellular Localization
- Secreted, Cytoplasmic granule
- Post Translation Modifications
- Poly-N-acetyllactosaminic carbohydrate moiety seems to be needed for TLR4 activation. (P02788-TRFL_HUMAN)
Glycosylation at Ser54, Asn156, Ser436, Asn497, and Asn642 (NX_P02788 [NX_P02788-1])
Ubiquitination at Lys423 and Lys435 (NX_P02788 [NX_P02788-1])
Modification sites at PhosphoSitePlus (P02788)
Glycosylation from GlyConnect TRFL_HUMAN (2842, 320)
Glycosylation from GlyGen (P02788) 5 sites, 158 N-linked glycans (4 sites), 2 O-linked glycans (1 site)
- Protein Refseq
- NP_001308050.1; NP_001186078.1
- Function
- Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. TRFL_HUMAN,P02788
[Lactotransferrin]: Major iron-binding and multifunctional protein found in exocrine fluids such as breast milk and mucosal secretions.
Has antimicrobial activity, which depends on the extracellular cation concentration.
Antimicrobial properties include bacteriostasis, which is related to its ability to sequester free iron and thus inhibit microbial growth, as well as direct bactericidal properties leading to the release of lipopolysaccharides from the bacterial outer membrane.
Can also prevent bacterial biofilm development in P.aeruginosa infection.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-003 | Recombinant Anti-human LTF VHH Single Domain Antibody | WB, ELISA, IP, FuncS | Llama VHH |
| HPAB-0194-YJ-VHH | Recombinant Camel Anti-LTF Single Domain Antibody (HPAB-0194-YJ-VHH) | ELISA, Immunoaffinity chromatography | Camel VHH |
| HPAB-0195-YJ-VHH | Recombinant Camel Anti-LTF Single Domain Antibody (HPAB-0195-YJ-VHH) | ELISA, Immunoaffinity chromatography | Camel VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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