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    Mouse Anti-MAPK1 Monoclonal Antibody (VS7-0425-WR346) (CAT#: VS7-0425-WR346)

    This product is a mouse IgG antibody that binds to human MAPK1. The antibody can be used for WB, IHC-P, IF, FC, and ELISA assays. It cross reacts with mouse.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/79930/1999_H7_3_selected.jpg
    Figure 2 IHC staining of human cerebral cortex
    Figure 2 IHC staining of human cerebral cortex
    (Immunohistochemical staining of human cerebral cortex shows moderate cytoplasmic and nuclear positivity in neuronal and glial cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3995/12643_B_9_5_selected.jpg
    Figure 3 IHC staining of human hippocampus
    Figure 3 IHC staining of human hippocampus
    (Immunohistochemical staining of human hippocampus shows strong cytoplasmic positivity in neuronal cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5700/21384_B_7_6_selected.jpg
    Normal Tissue
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Endothelial cells
    Staining:

    Medium

    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/
    membranous
    Glial cells
    Staining:

    Medium

    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/
    membranous
    Neuronal cells
    Staining:

    High

    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5700/21384_B_8_5.jpg
    Figure 5 Colon
    Figure 5 Colon
    (Endothelial cells
    Staining:

    High

    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/
    membranous
    Glandular cells
    Staining:

    High

    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5700/20815_A_9_3.jpg
    Figure 6 Liver
    Figure 6 Liver
    (Cholangiocytes
    Staining:

    High

    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/
    membranous
    Hepatocytes
    Staining:

    High

    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5700/20815_A_7_4.jpg
    Figure 7 Pancreas
    Figure 7 Pancreas
    (Exocrine glandular cells
    Staining:

    High

    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/
    membranous
    Pancreatic endocrine cells
    Staining:

    High

    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5700/20815_A_2_3.jpg
    Figure 8 Kidney
    Figure 8 Kidney
    (Cells in glomeruli
    Staining:

    Medium

    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/
    membranous
    Cells in tubules
    Staining:

    High

    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5700/20815_A_9_5.jpg
    Figure 9 Testis
    Figure 9 Testis
    (Cells in seminiferous ducts
    Staining:

    Medium

    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/
    membranous
    Leydig cells
    Staining:

    High

    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5700/20815_A_6_6.jpg
    Figure 10 Lymph node
    Figure 10 Lymph node
    (Germinal center cells
    Staining:

    High

    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/
    membranous
    Non-germinal center cells
    Staining:

    High

    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5700/20815_A_9_8.jpg
    RNA Expression
    Figure 11 RNA cell line category: Cell line enhanced (K-562)
    Figure 11 RNA cell line category: Cell line enhanced (K-562)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000100030-MAPK1
    Figure 11 RNA cell line category: Cell line enhanced (K-562)
    Figure 11 RNA cell line category: Cell line enhanced (K-562)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000100030-MAPK1

    Specifications

    • Immunogen
    • Recombinant human MAPK1 fragment expressed in E. Coli.
    • Host Species
    • Mouse
    • Type
    • Mouse IgG
    • Specificity
    • Human MAPK1
    • Species Reactivity
    • Human, Mouse
    • Molecule Class
    • Serine/Threonine Kinase
    • Applications
    • WB, IHC-P, IF, FC, ELISA
    • Conjugate
    • Unconjugated
    • Related Disease
    • Noonan syndrome 13 (NS13)

    Product Property

    • Clonality
    • Monoclonal
    • Purity
    • >95% as determined by SDS-PAGE and SEC-HPLC analysis, Ascitic fluid
    • Format
    • Liquid
    • Concentration
    • 1 mg/ml
    • Preservative
    • 0.03% sodium azide
    • Storage
    • Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Ice packs

    Applications

    • Application Notes
    • Western Blot: 1:500 - 1:2000
      Immunohistochemistry: 1:200 - 1:1000
      Flow Cytometry: 1:200 - 1:400
      Enzyme-linked Immunosorbent Assay: 1:10000

    Target

    • Alternative Names
    • MAPK1; mitogen-activated protein kinase 1; ERK; p38; p40; p41; ERK2; ERT1; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK
    • Long Name
    • Mitogen-activated protein kinase 1
    • Cellular Localization
    • Cell junction; Cytoplasm; Cytoskeleton; Membrane; Nucleus
    • Post Translation Modifications
    • Acetylation; Phosphoprotein; Ubl conjugation
    • Function
    • DNA-binding; Kinase; Repressor; Serine/threonine-protein kinase; Transferase

    Recommended Products

    Isotype Control

    Secondary Antibody

    Related Resources

    • Related Signaling Pathways
    • Related Diseases

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "MAPK1"

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    CAT Product Name Application Type
    MOB-1334z Mouse Anti-MAPK1 Recombinant Antibody (clone 22C9) ELISA, IHC, WB Mouse IgG2b
    MRO-1846-CN Rabbit Anti-MAPK1 Polyclonal Antibody (MRO-1846-CN) WB, IF, IHC, FC Rabbit IgG
    ZG-0315J Mouse Anti-MAPK1 Recombinant Antibody (ZG-0315J) WB, IHC, IF, ELISA Mouse IgG
    ZG-0455U Rabbit Anti-MAPK1 Recombinant Antibody (clone 10C7) ELISA, WB, IHC, IF Rabbit IgG
    VS7-0425-WR549 Mouse Anti-MAPK1 Monoclonal Antibody (clone 3F8) WB, IHC, FC Mouse IgG2b

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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