Mouse Anti-MAPK10 Monoclonal Antibody (clone 10E4A4)
CAT#: VS7-0425-WR349
This product is a mouse IgG1 antibody that binds to human MAPK10. The antibody 10E4A4 recognizes specific amino acid domain of human MAPK10 (aa28-233). It can be used for WB and ICC assays. It cross reacts with mouse.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human cerebral cortex
Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic and nuclear positivity in neuronal cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22625/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22625/48633_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22625/48633_A_9_3.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22625/48633_A_5_6.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enriched (AF22)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000109339-MAPK10
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Specifications
- Immunogen
- Recombinant human MAPK10 (aa28-233) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human MAPK10
- Species Reactivity
- Human, Mouse
- Clone
- 10E4A4
- Molecule Class
- Serine/Threonine Kinase
- Applications
- WB, ICC
- Conjugate
- Unconjugated
- Related Disease
- A chromosomal aberration involving MAPK10 has been found in a single patient with pharmacoresistant epileptic encephalopathy. Translocation t(Y;4)(q11.2;q21) which causes MAPK10 truncation
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis, Ascitic fluid
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunocytochemistry: 1:200 - 1:1000
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- MAPK10; JNK3 Alpha Protein Kinase; MAPK 10; Mitogen-Activated Protein Kinase 10; MAP Kinase 10; Stress-Activated Protein Kinase JNK3; JNK3; EC 2.7.11; Stress-Activated Protein Kinase 1b; PRKM10; SAPK1b; P54bSAPK
- Gene ID
- 5602
- UniProt ID
- P53779
- Long Name
- Mitogen-activated protein kinase 10
- Cellular Localization
- Cytoplasm; Membrane; Mitochondrion; Nucleus
- Post Translation Modifications
- Lipoprotein; Palmitate; Phosphoprotein
- Protein Refseq
- NP_001304996.1
- Function
- Kinase; Serine/threonine-protein kinase; Transferase
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Related Signaling Pathways
FcεR1 Signaling Pathway
TCR Signaling Pathway
Related Diseases
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "MAPK10"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2130z | Mouse Anti-MAPK10 Recombinant Antibody (clone 11A7) | WB, ELISA, FC, ICC, IF, IHC | Mouse IgG1 |
| MRO-0886-CN | Recombinant Rabbit Anti-MAPK10 Monoclonal Antibody (CBACN-332) | WB, IF, FC | Rabbit IgG |
| ZG-0524J | Mouse Anti-MAPK10 Recombinant Antibody (ZG-0524J) | WB, IF, ELISA | Mouse IgG |
| VS7-0425-WR348 | Mouse Anti-MAPK10 Recombinant Antibody (clone 2B10H12) | WB | Mouse IgG2a |
| VS7-0425-WR350 | Mouse Anti-MAPK10 Monoclonal Antibody (VS7-0425-WR350) | WB, IF, ICC, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2149 | Hi-Affi™ Recombinant Rabbit Anti-MAPK10 Monoclonal Antibody (DS2149AB) | WB, IHC, ICC, IP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1297 | Anti-MAPK10 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4227 | Anti-Human MAPK10 Immunohistochemistry Kit | IHC |
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