AbPlus™ Anti-MAPT Magnetic Beads (VS-0424-XY182)
CAT#: VS-0424-XY182
The AbPlus Anti-MAPT Magnetic Beads (VS-0424-XY182) is an innovative affinity resin which is bound with anti-MAPT specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of MAPT protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line BJ
Immunofluorescent staining of human cell line MCF7 shows localization to nuclear speckles & plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48895/1070_E6_2_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line BJ
Immunohistochemical staining of human appendix shows strong positivity in peripheral ganglia and nerve fibers.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69524/156431_A_3_2_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuropil
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/151/156500_B_8_5.jpg
Normal Tissue
Figure 4 Colon
Endocrine cells
Staining:
Medium
Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/151/156500_A_7_3.jpg
Normal Tissue
Figure 5 Kidney
Proximal tubules (cell body)
Staining:
Medium
Intensity: Moderate
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/151/156500_A_7_5.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (HDLM-2, SCLC-21H, T-47d)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186868-MAPT
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-MAPT specific antibody
- Target
- MAPT
- Immunogen
- Recombinant human MAPT
- Target Species
- Human
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
- Alternative Names
- TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; PPP1R103
- Gene ID
- 4137
- UniProt ID
- P10636
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "MAPT"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1215z | Mouse Anti-MAPT Recombinant Antibody (clone 44C4) | ICC, IF, IHC, WB | Mouse IgG1 |
| PABL-680 | Chicken Anti-MAPT Recombinant Antibody (clone pT231/pS235_1) | WB, ELISA, FACS, Block | Chicken IgY |
| MOB-1789MZ | Recombinant Mouse Anti-Human MAPT Antibody (clone IZC449-02) | ELISA | Mouse antibody |
| MRO-2389-CN | Recombinant Rabbit Anti-MAPT (phosphorylated Ser396) Monoclonal Antibody (CBACN-674) | WB, IF, IHC | Rabbit IgG |
| MRO-2390-CN | Recombinant Rabbit Anti-MAPT (phosphorylated Thr231) Monoclonal Antibody (CBACN-675) | WB, IHC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-305 | Chicken Anti-MAPT Recombinant Antibody; scFv Fragment | WB, ELISA, FuncS | Chicken scFv |
| PSBL-340 | Mouse Anti-MAPT Recombinant Antibody (clone AT8); scFv Fragment | ELISA, FuncS | Mouse scFv |
| PSBL-674 | Chicken Anti-MAPT Recombinant Antibody (clone pT231/pS235_1); scFv Fragment | WB, ELISA, FACS, Block | Chicken scFv |
| PSBL-705 | Mouse Anti-MAPT Recombinant Antibody (clone DC8E8); scFv Fragment | WB, IF, FuncS | Mouse scFv |
| HPAB-AP145-YC-S(P) | Human Anti-MAPT Recombinant Antibody; scFv Fragment (HPAB-AP145-YC-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0733MZ | Chicken Anti-TAU Polyclonal IgY | ICC, IF, IHC, WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-174 | Recombinant Mouse Anti-Tau5 Antibody | WB, ELISA, Neut, FuncS | IgG |
| PABX-174-S (P) | Recombinant Mouse Anti-Tau5 Antibody scFv Fragment | WB, ELISA, Neut, FuncS | scFv |
| PABX-174-F (E) | Recombinant Mouse Anti-Tau5 Antibody Fab Fragment | WB, ELISA, Neut, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2164 | Hi-Affi™ Recombinant Rabbit Anti-MAPT Monoclonal Antibody (DS2164AB) | IHC-P | IgG |
| MOR-4513 | Hi-Affi™ Recombinant Rabbit Anti-MAPT Monoclonal Antibody (TH21DS) | WB, IHC-P, FC | IgG |
| MOR-4714 | Hi-Affi™ Recombinant Rabbit Anti-MAPT Monoclonal Antibody (TH228DS) | WB, IF, ICC, IHC-P, FC | IgG |
| MOR-4715 | Hi-Affi™ Recombinant Rabbit Anti-MAPT Monoclonal Antibody (TH229DS) | WB, IF, ICC, IHC-P | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-090CN | Mouse Anti-MAPT Recombinant Antibody (NS-090CN) | WB, ELISA, IHC, IP, SPR, FuncS | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0042-WJ-F(E) | Human Anti-MAPT Recombinant Antibody; Fab Fragment (HPAB-0042-WJ-F(E)) | ELISA, WB | Humanized Fab |
| HPAB-0654YY-F(E) | Human Anti-MAPT Recombinant Antibody; Fab Fragment (HPAB-0654YY-F(E)) | Block, IHC | Humanized Fab |
| HPAB-0655YY-F(E) | Human Anti-MAPT Recombinant Antibody; Fab Fragment (HPAB-0655YY-F(E)) | Block, IHC | Humanized Fab |
| HPAB-0656YY-F(E) | Human Anti-MAPT Recombinant Antibody; Fab Fragment (HPAB-0656YY-F(E)) | Block, IHC | Humanized Fab |
| HPAB-0657YY-F(E) | Human Anti-MAPT Recombinant Antibody; Fab Fragment (HPAB-0657YY-F(E)) | Block, IHC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY121 | Human Anti-MAPT (clone IPN002) scFv-Fc Chimera | ELISA, FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4255 | Anti-MAPT Immunohistochemistry Kit | IHC | |
| VS-0525-XY4256 | Anti-Mouse MAPT Immunohistochemistry Kit | IHC | |
| VS-0525-XY4257 | Anti-Rat MAPT Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC120 | Recombinant Anti-MAPT (AA 220-224 x AA 506-511) Biparatopic Antibody, Tandem scFv (Clone 13A6 x Clone 19G10) | ELISA | Tandem scFv |
| VS-0525-YC121 | Recombinant Anti-MAPT (AA 506-511 x AA 537-541) Biparatopic Antibody, Tandem scFv (Clone 19G10 x Clone 10H8) | ELISA | Tandem scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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