Mouse Anti-MBP Recombinant Antibody (clone IN-1) (CAT#: FAMAB-0107-CN)
The monoclonal antibody IN-1 recognizes and neutralizes myelin-associated inhibitors of neurite growth.
Specific Inquiry
Inhib
Figure 1 Effect of the recombinant IN-1 Fab fragment or the intact IgM, respectively, on neurite outgrowth and fibroblast spreading in the presence of CNS myelin protein as inhibitory substrate.
Quantitative analysis of 3T3 fibroblast spreading.
IP
Figure 2 Immunoprecipitation of inhibitory activity by the IN-1 Fab fragment.
Silver-stained 6% polyacrylamide gel after SDS-PAGE under reducing conditions showing the antigenic material that was immunoprecipitated with either the IN-1 IgM or the recombinant Fab fragment.
IHC
Figure 3 Immunohistochemistry with the IN-1 Fab fragment on spinal cord sections.
Adjacent transverse sections of the spinal cord with the dorsal roots attached to it were diaminobenzidine-stained with an antibody against MBP (A, E), IN-1 IgM (B, F), IN-1 Fab fragment (C, G) and, as a control, with the second antibody conjugate alone (D, H).
Specifications
- Immunogen
- Rat CNS myelin 250 KD protein fraction
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgM, Κ
- Specificity
- Rat MBP
- Species Reactivity
- Rat
- Clone
- IN-1
- Applications
- WB, IF, IP, Block
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Related Resources
Asthma
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone IN-1"
See other products for "MBP"
Deglycosylated Antibody (Non-glycosylated IgGs)
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-174LC | Recombinant Anti-MBP Antibody (Non-glycosylated) | ELISA | Mouse antibody |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1267CT | Recombinant Mouse anti-Human MBP Monoclonal antibody (33) | IHC-Fr, IHC-P | |
| FAMAB-0217-CN | Recombinant Human Anti-MBP Antibody (E2) | WB, ELISA, IP | Human IgG1 |
| FAMAB-0218-CN | Recombinant Human Anti-MBP Antibody (F11) | WB, ELISA, IP | Human IgG1 |
| FAMAB-0219-CN | Recombinant Human Anti-MBP Antibody (E6) | WB, ELISA, IP | Human IgG1 |
| FAMAB-0220-CN | Recombinant Human Anti-MBP Antibody (D1) | WB, ELISA, IP | Human IgG1 |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0807MZ | Chicken Anti-MBP Polyclonal IgY | ICC, IF, IHC, WB | Chicken antibody |
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Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2184 | Hi-Affi™ Recombinant Rabbit Anti-MBP Monoclonal Antibody (DS2184AB) | IHC-FoFr, IHC-P | IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0216CQ-F(E) | Mouse Anti-MBP Recombinant Antibody (clone 845D3); Fab Fragment | ELISA, WB | Mouse Fab |
| FAMAB-0107-CN-F(E) | Mouse Anti-MBP Recombinant Antibody (clone IN-1); Fab Fragment | WB, IF, IP, Block | Mouse Fab |
| FAMAB-0217-CN-F(E) | Recombinant Human Anti-MBP Antibody Fab Fragment (E2) | WB, ELISA, IP | Human Fab |
| FAMAB-0218-CN-F(E) | Recombinant Human Anti-MBP Antibody Fab Fragment (F11) | WB, ELISA, IP | Human Fab |
| FAMAB-0219-CN-F(E) | Recombinant Human Anti-MBP Antibody Fab Fragment (E6) | WB, ELISA, IP | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0216CQ-S(P) | Mouse Anti-MBP Recombinant Antibody (clone 845D3); scFv Fragment | ELISA, WB | Mouse scFv |
| FAMAB-0107-CN-S(P) | Mouse Anti-MBP Recombinant Antibody (clone IN-1); scFv Fragment | WB, IF, IP, Block | Mouse scFv |
| FAMAB-0217-CN-S(P) | Recombinant Human Anti-MBP Antibody scFv Fragment (E2) | WB, ELISA, IP | Human scFv |
| FAMAB-0218-CN-S(P) | Recombinant Human Anti-MBP Antibody scFv Fragment (F11) | WB, ELISA, IP | Human scFv |
| FAMAB-0219-CN-S(P) | Recombinant Human Anti-MBP Antibody scFv Fragment (E6) | WB, ELISA, IP | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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