Human Anti-MCAM Recombinant Antibody (clone c3.19.1) (CAT#: HPAB-1176WJ)

This product is a human antibody targeting human MCAM. This antibody can be used in the diagnosis and treatment of disorders associated with increased activity of MCAM, in particular, tumors, such as melanomas.


Specific Inquiry
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  • Purity:
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  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Inhib

Figure 1 Shows that anti-MUC18 antibody, c3.19.1, inhibits the subcutaneous growth of WM-2264 tumor cells in vivo.

Figure 1 Shows that anti-MUC18 antibody, c3.19.1, inhibits the subcutaneous growth of WM-2264 tumor cells in vivo.

Inhib

Figure 2 Demonstrates that treatment with anti-MUC18 antibody, c3.19.1, prolongs the survival of WM-2664 mice bearing metastatic melanoma tumors.

Figure 2 Demonstrates that treatment with anti-MUC18 antibody, c3.19.1, prolongs the survival of WM-2664 mice bearing metastatic melanoma tumors.


Specifications

  • Immunogen
  • SK-MEL-28 cells
  • Host Species
  • Human
  • Type
  • Human IgG2
  • Specificity
  • Human MCAM
  • Species Reactivity
  • Human
  • Clone
  • c3.19.1
  • Applications
  • Inhib
  • Related Disease
  • Melanomas

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The MCAM antibody has been reported in applications of Inhibition.

Target

  • Alternative Names
  • CD146; MUC18

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone C3.19.1"

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Human Antibody

CAT Product Name Application Type
TAB-516CL Anti-Human MCAM Recombinant Antibody (ABX-MA1) WB, FuncS Antibody

Humanized Antibody

Rabbit Monoclonal Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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