Mouse Anti-MCL1 Recombinant Antibody (VS7-0425-WR366) (CAT#: VS7-0425-WR366)
This product is a mouse IgG antibody that binds to human MCL1. The antibody can be used for WB, IHC-P, IF, ICC, and ELISA assays.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8455/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8455/if_selected.jpg
Figure 2 Appendix
(High expression in appendix)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8455/22739_A_1_2_val_selected.jpg
(High expression in appendix)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8455/22739_A_1_2_val_selected.jpg
Figure 3 IHC staining of human stomach
(Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in parietal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_3_1_selected.jpg
(Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in parietal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_3_1_selected.jpg
Figure 4 IHC staining of human placenta
(Immunohistochemical staining of human placenta shows strong positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68195/ihc_selected.jpg
(Immunohistochemical staining of human placenta shows strong positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68195/ihc_selected.jpg
Figure 5 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_7_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_7_3.jpg
Figure 6 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_6_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_6_6.jpg
Figure 7 Thyroid gland
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_B_3_5.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_B_3_5.jpg
Figure 8 RNA cell line category: Cell line enriched (U-698)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000143384-MCL1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000143384-MCL1
Specifications
- Immunogen
- Recombinant human MCL1 fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human MCL1
- Species Reactivity
- Human
- Molecule Class
- Anti-Apoptotic Protein
- Applications
- WB, IHC-P, IF, ICC, ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis, Ascitic fluid
- Format
- Liquid
- Concentration
- 1 mg/ml
- Buffer
- PBS
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunohistochemistry: 1:200 - 1:1000
Immunofluorescence: 1:200 - 1:1000
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- MCL1; MCL1L; MCL1-ES; Bcl2-L-3; Myeloid Cell Leukemia 1; Mcl-1; Bcl-2-Like Protein 3; BCL2L3; Myeloid Cell Leukemia Sequence 1 (BCL2-Related); EAT; Myeloid Cell Leukemia ES; Bcl-2-Related Protein EAT/Mcl1; TM; Mcl1/EAT
- Gene ID
- 4170
- UniProt ID
- Q07820
- Long Name
- MCL1, BCL2 Family Apoptosis Regulator
- Cellular Localization
- Cytoplasm; Membrane; Mitochondrion; Nucleus
- Post Translation Modifications
- Isopeptide bond; Phosphoprotein; Ubl conjugation
- Protein Refseq
- NP_001184249.1
- Function
- Developmental protein
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1225CT | Recombinant Mouse anti-Human MCL1 Monoclonal antibody (49H4) | IHC-P | |
| MRO-2028-CN | Rabbit Anti-MCL1 Polyclonal Antibody (MRO-2028-CN) | IF, IHC | Rabbit IgG |
| ZG-0272C | Mouse Anti-MCL1 Recombinant Antibody (ZG-0272C) | WB, IHC, IF, ELISA | Mouse IgG |
| VS3-WK894 | Rabbit Anti-MCL1 Recombinant Antibody (VS3-WK894) | WB, ICC, IF, IHC, IP, FC | Rabbit IgG |
| VS7-0425-WR367 | Mouse Anti-MCL1 Recombinant Antibody (clone 8C6D4B1) | WB, IHC, ICC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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