Mouse Anti-MERTK Recombinant Antibody (clone 3D11G8) (CAT#: VS7-0425-WR377)
This product is a mouse IgG2b antibody that binds to human MERTK. The antibody 3D11G8 recognizes specific amino acid domain of human MERTK (AA:extra(21-220)). It can be used for WB, ICC, and FC assays.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75622/1740_F11_62_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75622/1740_F11_62_selected.jpg
Figure 2 Adrenal gland
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36196/75498_B_6_5.jpg
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36196/75498_B_6_5.jpg
Figure 3 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36196/75498_A_9_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36196/75498_A_9_4.jpg
Figure 4 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36196/75498_A_8_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36196/75498_A_8_5.jpg
Figure 5 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36196/75498_A_4_6.jpg
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36196/75498_A_4_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (CACO-2, Hep G2, HUVEC TERT2, RT4)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000153208-MERTK
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000153208-MERTK
Specifications
- Immunogen
- Recombinant human MERTK (AA:extra(21-220)) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- Human MERTK
- Species Reactivity
- Human
- Clone
- 3D11G8
- Molecule Class
- Mer/Axl/Tyro3 Receptor Kinase
- Applications
- WB, ICC, FC
- Conjugate
- Unconjugated
- Related Disease
- Retinitis pigmentosa 38 (RP38)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunocytochemistry: 1:200 - 1:1000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- MERTK; C-Mer; STK Kinase; C-Mer Proto-Oncogene Tyrosine Kinase; MER; EC 2.7.10.1; RP38; Proto-Oncogene C-Mer; MER Receptor Tyrosine Kinase; Tyrosine-Protein Kinase Mer; Receptor Tyrosine Kinase MerTK; Tyro12; C-Eyk; EC 2.7.10
- Gene ID
- 10461
- UniProt ID
- Q12866
- Long Name
- MER Proto-Oncogene, Tyrosine Kinase
- Cellular Localization
- Cell membrane; Membrane
- Post Translation Modifications
- Disulfide bond; Glycoprotein; Phosphoprotein
- Protein Refseq
- NP_006334.2
- Function
- Kinase; Receptor; Transferase; Tyrosine-protein kinase
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-4080z | Mouse Anti-MERTK Recombinant Antibody (clone 28A5) | WB, ELISA, IP | Mouse IgG1, κ |
| MOB-1466MZ | Recombinant Mouse Anti-Human MERTK Antibody (clone B422G0H4) | WB | Mouse antibody |
| HPAB-0215-CN | Mouse Anti-MERTK Recombinant Antibody (HPAB-0215-CN) | WB, ELISA | Mouse IgG |
| VS1-YJ136 | Mouse Anti-MERTK Recombinant Antibody (clone A311F9G3) | WB | Mouse IgG1, κ |
| VS3-WK909 | Rabbit Anti-MERTK Recombinant Antibody (VS3-WK909) | WB, IHC, IP | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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