Anti-MM46 Cell (clone W24V2-11-G) Recombinant Antibody Coupled Liposome (VS-1024-FY78) (CAT#: VS-1024-FY78)
This is a immunoglobulin M (IgM) antibody that is specifically targeting the mouse mammary tumor-associated antigen (MM antigen), can be effectively coupled with liposomes. This coupling allows the liposomes to selectively bind to MM⁺ tumor cells. This innovative approach offers a promising strategy for the preparation of antibody-coupled liposomes, paving the way for the development of targeted drug delivery systems.
More Infomation
Specifications
- Potential Clinical Applications
- Potential for use in mouse breast tumor research
- Immunoliposomes Method
- The study presents a method for preparing antibody-conjugated liposomes (immunoliposomes). Firstly, MBPE is synthesized through a reaction and liposomes are prepared in a nitrogen atmosphere along with other components. Next, aggregates are removed by centrifugation, and the first 4 ml of the liposome suspension is extracted. Then, it is reacted with a specific protein and treated with cysteine to block the maleimide groups. Finally, the liposomes are further purified by density gradient centrifugation, providing a targeted drug delivery system for subsequent experiments.
Product Composition
- Clone
- W24V2-11-G
- Antibody Type
- IgM
- Antibody Host
- Mouse
- Antibody Reactivity
- Mouse
- Antibody Description
- W24V2-11-G is produced by the fusion of mouse hybridoma cells (NS-1 mouse myeloma cells) with spleen cells of C3H/He x BALB/c F- mice, which previously developed a hyperimmune response to MM46 tumor cells. The monoclonal antibody secreted by W24V2-11-G is of IgM type and specifically recognizes a tumor-associated antigen (called MM antigen) distributed on the surface of a variety of breast tumor cells from C3H/He mice. According to the experimental results, the W24V2-11-G IgM antibody was detected in MM46 cells, but not in MM48 cells and normal spleen cells of C3H/He mice. Therefore, W24V2-11-G is a monoclonal IgM antibody against the surface antigen of MM46 tumor cells.
Product Property
- Storage
- See in the COA
- Storage Shelf Time
- See in the COA
Target Information
- Target
- MM46 Cell
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS-1024-FY78. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: ELISA, IHC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
-1.png)
Application: ELISA, FC, Block, SPR
Application: ELISA, FC, IF, WB
-1.jpg)
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
