Rabbit Anti-MMP8 Recombinant Antibody (clone R09-2E8) (CAT#: VS3-XY3431)
This product is a recombinant rabbit antibody targeting the human MMP8 (Matrix metallopeptidase 8). This antibody recognizes and binds to human MMP8. It also has cross-reactivity against mouse or rat MMP8. It has been determined using Western Blot, Immunohistochemistry-Paraffin, Immunoprecipitation, Flow cytometry, Immunocytochemistry or Immunofluorescence.
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SK-MEL-30
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21763/1984_B2_8_cr5e5901ef3d8ad_selected.jpg
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21763/1984_B2_8_cr5e5901ef3d8ad_selected.jpg
Figure 2 IHC staining of human spleen
(Immunohistochemical staining of human spleen shows strong cytoplasmic positivity in cells of red pulp.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21221/ihc_selected.jpg
(Immunohistochemical staining of human spleen shows strong cytoplasmic positivity in cells of red pulp.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21221/ihc_selected.jpg
Figure 3 Bone marrow
(Hematopoietic cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22935/50813_B_6_4.jpg
(Hematopoietic cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22935/50813_B_6_4.jpg
Figure 4 RNA cell line category: Cell line enriched (WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000118113-MMP8
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000118113-MMP8
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat MMP8
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R09-2E8
- Applications
- WB, IHC-P, ICC, IF, IP, FC
- Related Disease
- Preterm Premature Rupture of The Membranes; Gingivitis
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IF: 1/50-1/200
IP: 1/20
FC: 1/50-1/100
Target
- Alternative Names
- HNC; CLG1; MMP-8; PMNL-CL
- Gene ID
- 4317
- UniProt ID
- P22894
- Long Name
- Matrix metallopeptidase 8
- Cellular Localization
- Cytoplasmic granule, Secreted
- Post Translation Modifications
- Glycosylation at Asn54, Asn73, Asn112, Asn204, and Asn246 (NX_P22894 [NX_P22894-1])
Modification sites at PhosphoSitePlus (P22894)
Glycosylation from GlyGen (P22894) 5 sites
- Protein Refseq
- XP_011541137.1; XP_011541136.1
- Function
- Can degrade fibrillar type I, II, and III collagens.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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