CytoStream™ Rat Anti-Mouse Cd86 Recombinant Antibody (VS13-YC179)
CAT#: VS13-YC179
The CytoStream™ Rat Anti-Mouse Cd86 Recombinant Antibody is specific for mouse Cd86. Cd86 is a protein implicated in immune regulation and functions as a receptor ligand, enhancing processes like immunoglobulin production, NF-kappaB signaling, and T cell proliferation. It is expressed prominently in the central nervous system and retina and is studied for its roles in diseases like Guillain-Barré syndrome and autoimmune disorders such as Henoch-Schönlein purpura. The anti-Mouse Cd86 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (5 μL per 1x 10⁶ cells).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HDLM-2
Immunofluorescent staining of human cell line HDLM-2 shows localization to plasma membrane & centriolar satellites.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26802/1962_A12_6_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4319/11663_B_8_5.jpg
Normal Tissue
Figure 3 Lung
Macrophages Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4319/11663_A_1_4.jpg
Normal Tissue
Figure 4 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4319/11663_A_8_3.jpg
Normal Tissue
Figure 5 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4319/11663_A_9_8.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enriched (HDLM-2)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000114013-CD86
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Specifications
- Immunogen
- Recombinant mouse CD86.
- Host Species
- Rat
- Type
- Rat IgG2a
- Specificity
- Mouse Cd86
- Species Reactivity
- Mouse
- Applications
- FC
- Conjugate
- FITC
- Related Disease
- Henoch-Schoenlein purpura, Autoimmune disease, Chronic lymphocytic leukemia, Chronic obstructive pulmonary disease, and Systemic scleroderma
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS with 1% BSA.
- Preservative
- 0.05% Proclin 300
- Storage
- Store at 4°C for 12 months away from light. Do not freeze.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Flow cytometry (FC): 5 μL per 1x 10⁶ cells
Target
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Related Diseases
Rheumatoid Arthritis
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Graft-versus-Host Disease
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L002G | anti-CD86 immunotoxin 1G10 (IgG)-Gel | Cytotoxicity assay, Functional assay | |
| AGTO-L002S | anti-CD86 immunotoxin 1G10 (IgG)-Sap | Cytotoxicity assay, Functional assay | |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-361LC | Anti-Human CD86 Recombinant Antibody (chFun1) | IHC | Chimeric antibody (mouse/human) |
| TAB-361LC-S(P) | Anti-Human CD86 Recombinant Antibody scFv Fragment (chFun1) | IHC | Chimeric antibody (mouse/human) |
| TAB-361LC-F(E) | Anti-Human CD86 Recombinant Antibody Fab Fragment (chFun1) | IHC | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-419CQ | Mouse Anti-CD86 Recombinant Antibody (clone MM0101-7F35) | WB, Neut, FC, CyTOF® | Mouse IgG1 |
| NEUT-420CQ | Mouse Anti-CD86 Recombinant Antibody (clone CBL763) | WB, FC, CyTOF®, Neut | Mouse IgG1 |
| NEUT-421CQ | Mouse Anti-CD86 Recombinant Antibody (clone CBL024) | Neut, FC | Mouse IgG1 |
| NEUT-422CQ | Mouse Anti-CD86 Recombinant Antibody (clone IT2.2) | FC, FuncS, Neut | Mouse IgG2b, κ |
| NEUT-426CQ | Rat Anti-Cd86 Recombinant Antibody (clone PO3.1) | FC, FuncS, Neut | Rat IgG2b, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-423CQ | Rat Anti-Cd86 Recombinant Antibody (clone 2D10), Biotin | FC, IHC-Fr, IP, Block | Rat IgG2b, κ |
| NEUT-424CQ | Rat Anti-Cd86 Recombinant Antibody (clone GL-1) | FC, Block, IF, IHC, IP | Rat IgG2a, κ |
| NEUT-425CQ | Rat Anti-Cd86 Recombinant Antibody (NEUT-425CQ) | Block, FC, IHC-Fr, IP | Rat IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0588 | Hi-Affi™ Rabbit Anti-CD86 Recombinant Antibody (clone DS588AB) | WB, FC, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-1678CQ | Mouse Anti-CD86 Recombinant Antibody (clone OX48) | FC, IF | Mouse IgG1 |
| FAMAB-1762CQ | Mouse Anti-CD86 Recombinant Antibody (clone PO.3) | Block, FuncS, WB, FC, IHC | Mouse IgG2a |
| VS3-XY426 | Mouse Anti-CD86 Recombinant Antibody, FITC (clone 4ABU63) | FC, IHC, IP, IF, WB | Mouse IgG1 |
| VS3-XY427 | Mouse Anti-CD86 Recombinant Antibody, PE (clone 4ABU63) | FC, IHC, IP, IF, WB | Mouse IgG1 |
| VS3-XY428 | Mouse Anti-CD86 Recombinant Antibody (clone 4ABU63) | FC, IHC, IP, IF, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1586WJ-F(E) | Mouse Anti-CD86 Recombinant Antibody; Fab Fragment (clone 3D1) | ELISA, WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1586WJ-S(P) | Mouse Anti-CD86 Recombinant Antibody; scFv Fragment (clone 3D1) | ELISA, WB | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1509 | AbPlus™ Anti-Cd86 Magnetic Beads (VS-0724-YC1509) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY76 | CytoStream™ Mouse Anti-CD86 Recombinant Antibody (VS-0225-XY76) | FC | Mouse IgG1, kappa |
| VS-0225-XY77 | CytoStream™ Mouse Anti-CD86 Recombinant Antibody (VS-0225-XY77) | FC | Mouse IgG2b, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY10 | Human Anti-CD86 (clone Hu3D1) scFv-Fc Chimera | Inhib | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC683 | Recombinant Anti-CD86 Vesicular Antibody, EV Displayed (VS-0425-YC683) | Block, ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1235 | Anti-Mouse CD86 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1236 | Anti-Rat CD86 Immunohistochemistry Kit | IHC |
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