CytoStream™ Rat Anti-Mouse Cd86 Recombinant Antibody (VS13-YC179) (CAT#: VS13-YC179)
The CytoStream™ Rat Anti-Mouse Cd86 Recombinant Antibody is specific for mouse Cd86. Cd86 is a protein implicated in immune regulation and functions as a receptor ligand, enhancing processes like immunoglobulin production, NF-kappaB signaling, and T cell proliferation. It is expressed prominently in the central nervous system and retina and is studied for its roles in diseases like Guillain-Barré syndrome and autoimmune disorders such as Henoch-Schönlein purpura. The anti-Mouse Cd86 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (5 μL per 1x 10⁶ cells).
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HDLM-2
(Immunofluorescent staining of human cell line HDLM-2 shows localization to plasma membrane & centriolar satellites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26802/1962_A12_6_selected.jpg
(Immunofluorescent staining of human cell line HDLM-2 shows localization to plasma membrane & centriolar satellites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26802/1962_A12_6_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4319/11663_B_8_5.jpg
(Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4319/11663_B_8_5.jpg
Figure 3 Lung
(Macrophages Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4319/11663_A_1_4.jpg
(Macrophages Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4319/11663_A_1_4.jpg
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4319/11663_A_8_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4319/11663_A_8_3.jpg
Figure 5 Lymph node
(Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4319/11663_A_9_8.jpg
(Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4319/11663_A_9_8.jpg
Figure 6 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000114013-CD86
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000114013-CD86
Specifications
- Immunogen
- Recombinant mouse CD86.
- Host Species
- Rat
- Type
- Rat IgG2a
- Specificity
- Mouse Cd86
- Species Reactivity
- Mouse
- Applications
- FC
- Conjugate
- FITC
- Related Disease
- Henoch-Schoenlein purpura, Autoimmune disease, Chronic lymphocytic leukemia, Chronic obstructive pulmonary disease, and Systemic scleroderma
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS with 1% BSA.
- Preservative
- 0.05% Proclin 300
- Storage
- Store at 4°C for 12 months away from light. Do not freeze.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Flow cytometry (FC): 5 μL per 1x 10⁶ cells
Target
- Alternative Names
- B7; B70; MB7; B7-2; B7.2; CLS1; Ly58; ETC-1; Ly-58; MB7-2; Cd28l2; TS/A-2
- Gene ID
- 12524
- UniProt ID
- P42082
- Long Name
- CD86 antigen
Recommended Products
Secondary Antibody
Isotype Control
Related Resources
Rheumatoid Arthritis
Systemic Lupus Erythematosus
Allograft Rejection
Autoimmune Thyroid Disease
Graft-versus-Host Disease
Maturity Onset Diabetes of the Young
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L002G | anti-CD86 immunotoxin 1G10 (IgG)-Gel | Cytotoxicity assay, Functional assay | |
| AGTO-L002S | anti-CD86 immunotoxin 1G10 (IgG)-Sap | Cytotoxicity assay, Functional assay | |
| AGTO-L002O | anti-CD86 immunotoxin 1G10 (IgG)-Bouganin | Cytotoxicity assay, Functional assay |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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